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小儿重症腺病毒肺炎混合感染特征及高危因素分析 被引量:22

Characteristics and risk factors of mixed infection of severe adenovirus pneumonia in children
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摘要 目的分析小儿重症腺病毒肺炎混合感染特征、高危因素,提高腺病毒重症肺炎的管理水平。方法医院共诊断腺病毒肺炎88例,采用回顾性调查分析方法,描述统计患儿混合感染情况,将重症患儿分为重症组,轻症患儿纳入对照组,进行因素分析。结果重症率47.73%;重症者其他病原体感染占90.48%,检出其他病原株78株,革兰氏阴性菌38.46%(30/78),病毒37.18%(29/78)革兰氏阳性菌10.26%(8/78),真菌、支原体、衣原体占14.10%(11/78);热程[OR=1.104,95%Cl(1.520~5.277)]、嗜睡精神差[OR=4.472,95%Cl(1.270~6.271)]、先天性气道发育异常[OR=11.0453,95%Cl(4.521~26.371)]、先天性心脏病[OR=3.254,95%Cl(1.812~5.572)]成为独立危险因素(P<0.05)。结论小儿重症腺病毒肺炎混合感染特征可见多种类型的病原体,革兰氏阳性菌、病毒多见,重症化与热程、精神、先天性气道与心脏疾病有关。 Objective To analyze the characteristics and high risk factors of mixed infection of severe adenovirus pneumonia in children,and to improve the management level of severe pneumonia.Methods The hospital diagnosis of adenovirus pneumonia in88cases,using the method of retrospective analysis,statistical description of mixed infection in children with severe,patients were divided into severe group,mild cases in the control group,factor analysis.Results The rate of severe infection of other pathogens accounted for47.73%;90.48%severe cases,the detection of other pathogenic strains and78strains of gram negative bacteria,virus38.46%(30/78)37.18%(29/78)(8/78)10.26%gram positive bacteria,fungus,mycoplasma and Chlamydia accounted for14.10%(11/78);thermal process[OR=1.104,95%Cl(1.520-5.277),somnolence the spirit of[OR=4.472,95%Cl(1.270-6.271),congenital airway abnormalities of[OR=11.0453,95%Cl(4.521-26.371),congenital heart disease[OR=3.254,95%Cl(1.812-5.572)as independent risk factors(P<0.05).Conclusion The mixed infection of severe adenovirus pneumonia in children can see many kinds of pathogens,gram positive bacteria and viruses,severe and heat,mental,congenital airway and heart disease.
作者 崔小文 Cui Xiao-wen(Zhangjiajie city People's Hospital, Zhangjiajie, Hunan, 427000, China)
出处 《当代医学》 2017年第24期16-18,共3页 Contemporary Medicine
关键词 重症肺炎 小儿 腺病毒 混合感染 危险因素 Severe pneumonia Children Adenovirus Mixed infection Risk factors
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