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药物涂层球囊在下肢动脉硬化闭塞性疾病中的应用进展 被引量:13

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摘要 下肢动脉硬化闭塞性疾病(arteriosclerosisobliterans,ASO)是动脉粥样硬化的局部表现,好发于下肢股腘动脉和膝下动脉,未经正规、有效治疗,最终进展为严重肢体缺血(criticallimbischemia,CLI)。随着社会生活水平的提高和人口老龄化,ASO的发病率逐年增加,在年龄大于70岁的人群中,患病率高达15%~20%[1]。普通球囊血管成形术(plainoldballoonangioplasty,POBA)通过球囊或配合支架,扩张狭窄或闭塞段,达到血管再通的目的,但术后1年再狭窄率高达40%~60%[2-3],往往需要二次手术治疗。近年来,基于药物涂层球囊(drug-coatedballoon,DCB)的新技术开始应用于ASO和POBA术后再狭窄,正逐渐成为下肢动脉疾病介入治疗领域的一个研究热点。
作者 孙利坤 王兵
出处 《实用医学杂志》 CAS 北大核心 2017年第14期2415-2418,共4页 The Journal of Practical Medicine
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