摘要
目的评价气管镜引导下多方法联合介入技术在恶性气道狭窄治疗中的有效性及安全性。方法选择我院内镜中心2013年8月～2015年10月收治的52例恶性肿瘤所致气道狭窄患者，根据气道阻塞程度、类型等，分别或联合给予高频电治疗、氩等离子体凝固术(APC)、冷冻、支架植入术等介入治疗，比较治疗前后呼吸困难指数、KPS评分及氧合指数(PaO2/FiO2)等指标的变化，对临床疗效进行总体判定分析。结果52例恶性气道狭窄患者经介入治疗后，气道狭窄程度及主观症状均较术前显著改善，治疗前后呼吸困难指数评分、KPS评分及氧合指数指标均有统计学差异(P<0.05)，治疗总有效率达到100%；且无1例气胸、血管病变、心脏骤停等严重并发症发生。结论对恶性肿瘤所致气道狭窄患者，实施气管镜引导下多方法联合介入治疗方案，可快速通畅气道、有效保证气促改善，且不良反应少，具有较好的临床应用价值。
Objective To evaluate the efficacy and safety of multiple methods combined with interventional techniques in the treatment of malignant airway stenosis.Methods:52cases of airway stenosis caused by malignant tumor in our hospital from201510to20138were included.All patients were according to the degree and types of airway obstruction,respectively or combined to give interventional treatment of high-frequency electric therapy,argon plasma coagulation(APC),cryotherapy,stent implantation.The changes of respiratory difficulty index,KPS score and oxygenation index(PaO2/FiO2)were compared before and after treatment in52cases,and the clinical effect was analyzed.Results:The airway stenosis degree and subjective symptoms were all significantly improved compared with preoperative in52cases of malignant airway stenosis after interventional therapy.Before and after the treatment of respiratory difficulty index,KPS score and oxygen index were statistically significant(P<0.05)difference.The total effective rate was100%.No serious complications occurred such as pneumothorax,vascular disease,cardiac arrest and other serious complications.Conclusions:The patients with malignant tumor induced airway stenosis with bronchoscopy guided combined with interventional therapy could be fast unobstructed airway,effective guarantee to improve shortness of breath,and adverse reactions less,with well clinical application value.
出处
《世界中医药》
CAS
2017年第A01期411-411,413,共2页
World Chinese Medicine
关键词
气管镜
恶性肿瘤
气道狭窄
联合介入
Bronchoscopy
malignant tumor
airway stenosis
combined intervention
