摘要
目的:分析高龄心脑血管病患者口服阿司匹林的疗效与安全性。方法:选择2015年5月—2017年1月60例高龄心脑血管病患者并随机分组。常规组单纯进行常规治疗,阿司匹林组在常规组基础上给予阿司匹林治疗。比较两组高龄心脑血管病治疗效果;联合终点事件发生率、主要终点事件发生率、血栓事件发生率、出血事件发生率。结果:阿司匹林组高龄心脑血管病治疗效果高于常规组,P<0.05;阿司匹林组联合终点事件发生率、主要终点事件发生率、血栓事件发生率均显著低于常规组,P<0.05;阿司匹林组出血事件发生率高于常规组,但差异不显著,P>0.05。结论:高龄心脑血管病患者口服阿司匹林的疗效好,可有效降低不良事件发生,改善患者预后,用药的安全性较好,除了个别可出现出血事件,无其他明显不良反应,值得推广。
Objective:To analyze the curative effect and security of the senile cardio-cerebrovascular disease in patients with oral aspirin.Methods:in May2015-January2017,60patients with senile cardio-cerebrovascular disease were randomly divided into two groups.The regular treatmentgroup was with conventional therapy alone,and the aspirin group was given aspirin therapy on the basis of conventional group.Senile cardiocerebrovasculardisease treatment effect,joint outcome events,the primary end point event rate,incidence of thrombotic events,the incidence ofbleeding events were compared between two groups.Results:Senile cardio-cerebrovascular disease treatment effect in the aspirin group is betterthan normal group(P<0.05);The finish events,the primary end point events incidence,the incidence of thrombotic events in the aspirin group weresignificantly lower than normal group(P<0.05);Aspirin bleeding events is higher than normal group,but with no significant difference(P>0.05).Conclusion:The curative effect of senile cardio-cerebrovascular disease in patients with oral aspirin treatment is good.It can effectively reduce theadverse events,and improve the prognosis of patients,with better safety.In addition,there is no other obvious adverse reactions,thus it is worthy ofpromotion.
作者
曹宝平
李芳伶
CAO Bao-ping;LI Fang-ling(Ganzhou People's Hospital physical examination department,Ganzhou Jiangxi 341000,China;Department of pharmacy; Ganzhou People's Hospital,Ganzhou Jiangxi 341000,China)
出处
《药品评价》
CAS
2017年第8期47-49,共3页
Drug Evaluation
关键词
心脑血管病
高龄患者
口服阿司匹林
疗效
安全性
Cardio-Cerebrovascular Disease
Aged Patients
Oral Aspirin
Curative Effect
Security
