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不同腹腔镜剥离术式对子宫内膜异位症患者性激素、窦卵泡数及卵巢体积的影响 被引量:25

Impact of different kinds of laparoscopic surgery on sex hormone, antral follicle count and ovarian volume of patients with EMs
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摘要 目的探讨腹腔镜下常规钝性剔除与改良锐性剥离术式对子宫内膜异位症(EMs)患者性激素、窦卵泡数(AFC)及卵巢体积的影响。方法选取该院2013年1月-2016年4月收治EMs患者共100例,按随机数字表法分为对照组(50例)和观察组(50例),分别给予腹腔镜下常规钝性剔除与改良锐性剥离术式治疗;比较两组患者剥除病灶厚度、卵巢皮质剥除率、卵巢皮质剥除厚度、手术前后血清性激素水平、患侧卵巢AFC及卵巢体积。结果两组患者卵巢窝部位剥除病灶厚度、卵巢皮质剥除率及卵巢皮质剥除厚度比较差异无统计学意义(P>0.05);观察组患者中间部位剥除病灶厚度和卵巢皮质剥除厚度均明显低于对照组(P<0.05);观察组患者卵巢门剥除病灶厚度、卵巢皮质剥除厚度和卵巢皮质剥除率均明显低于对照组(P<0.05);两组患者手术前后性激素水平比较差异无统计学意义(P>0.05);观察组患者手术前后患侧卵巢AFC水平比较差异无统计学意义(P>0.05);对照组患者术后患侧卵巢AFC水平明显低于术前(P<0.05);两组患者术后卵巢体积均明显小于术前(P<0.05);观察组患者术后卵巢体积明显大于对照组(P<0.05)。结论腹腔镜下改良锐性剥离术式治疗EMs患者可有效减少卵巢门皮质剥除量,降低初级和次级卵泡丢失程度,价值优于常规钝性剥离术式。 Objective To investigate the impact of different kinds of laparoscopic surgery includingconventional blunt elimination and modified acute elimination on sex hormone,antral follicle count and ovarianvolume of patients with endometriosis(EMs).Methods100patients with EMs were chosen from January2013to April2016and randomly divided into control group(50patients)with conventional blunt elimination andobservation group(50patients)with modified acute elimination;and the thickness of elimination lesion,the removalrate of ovary cortex,the thickness of ovarian cortex,the level of serum sex hormones,the AFC number of affectedside and the volume of ovary before and after operation of the two groups were compared.Results There wasno significant difference in the thickness of lesion elimination,the removal rate and removed thickness of ovariancortical between the two groups(P>0.05).The thickness of lesion elimination and the thickness of ovarian cortexin middle position of observation group were significantly lower than that in control group(P<0.05).The thicknessof lesion elimination,removed thickness of ovarian cortical and the removal rate of ovary cortex in hilus ovarii inobservation group were significantly lower than that in control group(P<0.05).There was no significant differencein the levels of serum sex hormones before and after treatment between the two groups(P>0.05).There was no significant difference in the levels of AFC number of affected side before and after treatment(P>0.05).The levels ofAFC number of affected side in hilus ovarii of control group after treatment were significantly lower than that beforetreatment(P<0.05).The volume of ovary of both groups after treatment were significantly lower than that beforetreatment(P<0.05).The volume of ovary of observation group after treatment were significantly higher than that incontrol group(P<0.05).Conclusion Compared with conventional blunt elimination,modified acute elimination inthe treatment of patients with EMs can efficiently shorten the operation time,reduce
作者 黄晓花 韩毓 韦佩佳 赵海燕 谢招娣 Xiao-hua Huang;Yu Han;Pei-jia Wei;Hai-yan Zhao;Zhao-di Xie(Department of Gynecology and Obstetrics, the Forth People's Hospital,Haikou, Hainan 571100, China)
出处 《中国内镜杂志》 北大核心 2017年第5期74-78,共5页 China Journal of Endoscopy
关键词 腹腔镜 子宫内膜异位症 手术方式 性激素 窦卵泡数 卵巢体积 laparoscopy endometriosis, EMs operation mode sex hormone antral follicle count ovarian volume
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