摘要
目的:研究骨氏葆方治疗膝骨关节炎的有效性、安全性及对骨代谢指标的影响。方法:选取我院收治的100例膝骨关节炎患者为研究对象,随机分成两组,各50例。对照组采用盐酸氨基葡萄糖胶囊治疗,观察组口服骨氏葆方治疗。比较两组患者症状评分及相关指标变化。结果:治疗后两组患者降钙素及骨型碱性磷酸酶指标相比,无明显差异(P>0.05);观察组血沉指标明显低于对照组,差异显著(P<0.05);治疗后两组症状评分均显著降低,且观察组降低趋势大于对照组,差异显著(P<0.05);两组患者治疗中均未出现严重不良反应,且所有患者进行血常规、肝肾功能的动态监测,均未发现明显异常变化,两组治疗前后肝肾功能指标相比均无明显差异(P>0.05)。结论:骨氏葆方治疗膝骨关节炎效果显著,安全性高,具有较高的临床应用价值。
Objective:To study the efficacy and safety of the Gushibao prescription on knee osteoarthritis and bone metabolism.Methods:100patients were randomly divided into two groups,50cases in each.The control group was treated with aminoglucose hydrochloride;the observation group was treated with the Gushibao prescription.Results:There was no significant difference in calcitonin and bone alkaline phosphatase between groups(P>0.05).The ESR in the observation group was significantly lower,with a significant difference(P<0.05).The scores in groups were significantly lower;and that in the observation group was more significant(P<0.05).There was no serious adverse reaction.The blood,liver and kidney function of all patients showed no significant differences(P>0.05).Conclusion:The Gushibao prescription on knee osteoarthritis is effective and safe,and shows high clinical value.
出处
《中医临床研究》
2017年第7期11-13,共3页
Clinical Journal Of Chinese Medicine
基金
河北省中医药管理局科研课题
编号为2016166
关键词
骨氏葆方
膝骨关节炎
安全性
The Gushibao prescription
Knee osteoarthritis
Safety
