摘要
目的给予膀胱肿瘤患者术后吉西他滨联合膀胱序贯治疗,分析其护理要点。方法 50例膀胱肿瘤患者,分为研究组和参照组,每组25例。参照组患者应用羟基喜树碱灌注治疗,研究组患者在参照组治疗基础上应用吉西他滨联合膀胱序贯治疗。比较两组患者的2年肿瘤无复发率、膀胱癌进展率。结果研究组患者2年肿瘤无复发率为76.00%(19/25),参照组患者2年肿瘤无复发率为44.00%(11/25),研究组患者2年肿瘤无复发率高于参照组,差异具有统计学意义(χ~2=5.3333,P<0.05);研究组患者膀胱癌进展率为4.00%(1/25),参照组患者膀胱癌进展率为8.00%(2/25),两组患者膀胱癌进展率比较差异无统计学意义(χ~2=0.3546,P>0.05)。结论给予膀胱肿瘤患者术后吉西他滨联合膀胱序贯治疗的临床疗效较为理想,同时辅以护理干预可以显著提升2年肿瘤无复发率。
Objective To apply postoperative gemcitabine combined with bladder sequential therapy for bladder tumor patients, and to analyze key points in nursing. Methods A total of 50 patients with bladder tumor were randomly divided into research group and control group, with 25 cases in each group. The control group received hydroxycamptothecine perfusion for treatment, and the research group received gemcitabine combined with bladder sequential therapy on the basis of therapy in the control group. Comparison was made on 2-year nonrecurrence rate of tumor, and progress rate of bladder cancer between the two groups. Results The research grouphad 2-year non-recurrence rate of tumor as 76.00% (19/25), and the control group had 2-year non-recurrencerate of tumor as 44.00% (11/25). The research group had higher 2-year non-recurrence rate of tumor than the control group, and their difference had statistical significance (χ2=5.3333, P<0.05). The research group had progress rate of bladder cancer as 4.00% (1/25) and the control group had progress rate of bladder cancer as 8.00%(2/25). Their difference of progress rate of bladder cancer between the two groups had no statistical significance (χ2=0.3546, P>0.05). Conclusion Implement of postoperative gemcitabine combined with bladder sequential therapy for bladder tumor patients provides ideal effect in clinical treatment. Combining with nursing intervention,this method can remarkably improve 2-year non-recurrence rate of tumor.
作者
宋瑶
张鼐鹏
王磊
SONG Yao;ZHANG Nai-peng;WANG Lei(Hongqi Hospital of Mudanjiang Medical University, Mudanjiang 157000, China)
出处
《中国现代药物应用》
2017年第5期126-127,共2页
Chinese Journal of Modern Drug Application
关键词
膀胱肿瘤
吉西他滨
序贯
护理
Bladder tumor
Gemcitabine
Sequential
Nursing
