摘要
目的:探讨血清肿瘤标志物在肺癌辅助诊断中的临床应用价值。方法:采用化学发光法对肺癌组67例患者、肺良性疾病组42例患者以及正常对照组的56例的血清SCC、NSE、CEA、CYFRA21-1、pro-GRP 5种肿瘤标志物进行化学检测及统计学分析。结果:NSE、CEA、CYFRA21-1、pro-GRP在肺癌组明显高于正常对照组和肺良性疾病组(P<0.05)。小细胞肺癌中NSE、pro-GRP的水平明显高于其他类型肺癌(P<0.05)。结论:血清肿瘤标志物在肺癌辅助诊断的临床应用中,对肺癌的辅助诊断呈现较高的特异性,尤其是CYFRA21-1在鳞癌的辅助诊断中临床应用价值较高。
Objective:To explore the clinical application value of serum tumor markers in the auxiliary diagnosis of lung cancer.Methods:The serum SCC,NSE,CEA,CYFRA21-1,pro-GRP five tumor markers of 67 patients in the lung cancer group,42 patientsin the benign lung disease group and 56 cases in the normal control group were given chemical detection by using chemicalluminescence method,and they were given statistical analysis.Results:NSE,CEA,CYFRA21-1 and pro-GRP in the lung cancergroup were significantly higher than those of the normal control group and the benign lung disease group(P<0.05).The levels ofNSE and pro-GRP in the small cell lung cancer were significantly higher than those of other types of lung cancer(P<0.05).Conclusion:In the clinical application of serum tumor markers in the auxiliary diagnosis of lung cancer,the auxiliary diagnosis oflung cancer shows a high specificity,especially the clinical application value of CYFRA21-1 in the auxiliary diagnosis ofsquamous cell carcinoma is high.
作者
李继轩
Li Jixuan(Pengshui County People's Hospital of Chongqing City 409600)
出处
《中国社区医师》
2016年第29期135-136,共2页
Chinese Community Doctors
关键词
血清肿瘤标志物
肺癌
辅助诊断
Serum tumor markers
Lung cancer
Auxiliary diagnosis
