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奥曲肽、垂体后叶素和奥美拉唑治疗门脉高压性胃病急性出血的对照研究 被引量:1

Comparative study of octreotide,pituitrin and omeprazole in the treatment of acute bleeding portal hypertensive gastropathy
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摘要 目的:探讨奥美拉唑、垂体后叶素、奥曲肽在门脉高压性胃病急性出血中的不同治疗效果。方法:收治门脉高压性胃病急性出血患者90例,按照患者使用的不同治疗药物进行分组:使用奥曲肽的30例患者为A组,使用垂体后叶素的30例患者为B组,使用奥美拉唑的30例患者为C组。结果:止血成功率:A组100%,B组63.33%,C组56.67%;输血量:A组(477±316)m L,B组(696±454)m L,C组(619±57)m L;不良反应率:A组10%,B组40%,C组3.33%。三组之间差异均有统计学意义(P<0.05)。结论:对于PHG急性出血,奥曲肽兼具显著疗效与安全性,奥美拉唑疗效尚可但安全性高。 Objective:To explore the different effect of omeprazole,posterior pituitrin,octreotide in the treatment of acute bleedingportal hypertensive gastropathy.Methods:90 patients with acute bleeding portal hypertensive gastropathy were selected.Accordingto the patients with the different treatments,they were divided into three groups:the use of octreotide in 30 patients with as the Agroup,used the posterior blade element of 30 patients as the B group,omeprazole for 30 cases of patients as the C group.Results:Hemostasis success rate:A group was 100% ;B group was 63.33% ;C group was 56.67% .Blood transfusion volume:A groupwas(477±316)mL;B group was(696±454)mL;C group was(619±57)mL.Adverse reaction rate:A group was 10% ;B group was40%;C group was 3.33%.There were statistically significant differences among three groups(P<0.05).Conclusion:For PHG acutebleeding,octreotide has significant efficacy and safety.Efficacy of omeprazole is good but safety is high.
作者 彭讲美
出处 《中国社区医师》 2016年第29期53-54,共2页 Chinese Community Doctors
关键词 奥美拉唑 垂体后叶素 奥曲肽 门脉高压性胃病 急性出血 Omeprazole Posterior pituitary hormone Octreotide Portal hypertensive gastric disease Acute hemorrhage
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