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介入溶栓治疗下肢深静脉血栓的效果评价及预后影响因素分析 被引量:9

Analysis of factors that impacts prognostic of interventional therapy for DVT
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摘要 目的分析介入溶栓治疗下肢深静脉血栓(DVT)的临床效果及影响预后的相关因素。方法回顾性分析2012年7月—2015年6月收治的65例DVT形成患者的临床资料,男27例,女38例,平均年龄59.9岁,其中予单纯药物治疗16例、药物+置管溶栓治疗23例、药物+置管溶栓+机械溶栓联合治疗26例;44例患者行滤器置入术。结果 65例患者经治疗后,截止随访治疗有效52例,无效及复发13例,平均住院时间16.2 d,围手术期死亡0例。Logistic回归分析显示疾病病程和治疗方法是影响DVT预后的影响因素,多元回线性归分析显示住院时间与病程、血栓解剖位置、滤器有线性回归关系(P<0.05)。结论疾病病程和治疗方法是影响DVT患者预后的影响因素,病程、血栓解剖位置、治疗方法及滤器是影响住院时间的因素,早期合适的诊治,可降低DVT的再发及并发症。 Objective This paper is to analyze the outcome and risk factors of interventional therapy for lower extremity deep venous thrombosis. Methods From July 2012 to June 2015, 65 patients (27 men and 38 women) underwent interventional therapy for deep venous thrombosis of lower extremity. 16 patients underwent conservative therapy, 23 patients underwent catheter-directed thrombolysis, 26 patients underwent mechanical thrombolysis plus catheter-directed thrombolysis. Results Follow up duration are 1 to 30 months. During the follow up duration, 13 patients replase or fail treated, the cured rate was 80.0%. The average hospitalization time is 16.2 d.The result of single factor study and logistic regression analysis show that the treatment methods and the stages of thrombosis are the prognosis factors. Multivariate multiple linear regression analysis show that the stages and location of thrombosis, and the filter influence the duration of hospitalization. Conclusions The treatment methods and the stages of thrombosis influence the prognosis of DVT with thrombolysis therapy. The stages ,locations of thrombosis and the filter will influence the duration of hospitalization.
作者 黄晨 冯惠岗 庄炜钊 郭惠庄 黄益 胡佩玲 麦健云 陈汉威 唐郁宽 Huang Chen;Feng Huigang;Zhuang Weizhao;Guo Huizhuang;Huang Yi;Hu Peiling;Mai Jianyun;Chen Hanwei;Tang Yukuan(Department of Interventional Radiology, Guangzhou Panyu Central Hospital, Guangzhou 511400, China)
出处 《中华介入放射学电子杂志》 2016年第1期27-31,共5页 Chinese Journal of Interventional Radiology:electronic edition
关键词 下肢深静脉血栓 溶栓 住院时间 预后 介入治疗 Lower extremity deep venous thrombosis Interventional thrombolysis Duration of hospitalization Prognosis Interventional treatment
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