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腹腔镜胆囊切除术对急性胆囊炎患者免疫功能的影响 被引量:3

Effect of laparoscopic cholecystectomy on the immune function of patients with acute cholecystitis
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摘要 目的:探讨腹腔镜胆囊切除术对急性胆囊炎患者免疫功能的影响。方法:收治急性胆囊炎患者100例,随机分为观察组和对照组各50例,对照组采用传统开腹胆囊切除术治疗,观察组采用腹腔镜胆囊切除术治疗,比较两组的治疗效果。结果:手术后第3天,两组免疫蛋白水平均较手术前下降,但是观察组Ig G、Ig A、Ig M水平明显高于对照组(P<0.05);观察组手术后的外周血CD3、CD4、CD8活性恢复水平优于对照组(P<0.05)。结论:实施腹腔镜胆囊切除术对急性胆囊炎患者免疫功能影响小,具有操作简便、安全性高等优势。 Objective:To explore the effect of laparoscopic cholecystectomy on the immune function of patients with acutecholecystitis.Methods:100 patients with acute cholecystitis were selected.They were randomly divided into the observation groupand the control group with 50 cases in each.The patients in the control group were given the traditional open cholecystectomyresection.The patients in the observation group was given laparoscopic gallbladder resection.We compared the therapeutic effectof two groups.Results:At the third day after surgery,the levels of the immune protein in two groups were decreased,but the IgG,IgAand IgM levels in the observation group were significantly higher than those in the control group(P<0.05).In the observationgroup,the recovery levels of CD3,CD4 and CD8 activity in peripheral blood after operation were better than those in the controlgroup(P<0.05).Conclusion:The effect of laparoscopic cholecystectomy on the immune function of patients with acute cholecystitiswas small.It had the advantages of easy operation,high security and so on.
作者 刘大龙 曹农 Liu Dalong;Cao Nong(Department of General Surgery,the First People's Hospital of Lanzhou City,Gansu Province 730000)
出处 《中国社区医师》 2016年第8期23-24,共2页 Chinese Community Doctors
关键词 腹腔镜胆囊切除术 急性胆囊炎 免疫功能 Laparoscopic cholecystectomy Acute cholecystitis Immune function
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