摘要
目的:探讨在糖尿病临床试验中,糖化血红蛋白(Hb A1c)检测的诊断价值。方法:收治糖尿病患者90例作为观察组,同时将健康体检者90例作为对照组,两组分别采用免疫透射比浊法和葡萄糖氧化酶法测定Hb A1c与空腹血糖(FBG),对比分析Hb A1c与空腹血糖水平及糖尿病并发症发生率的相关性。结果:糖尿病组空腹血糖及Hb A1c均显著高于健康对照组;随Hb A1c水平的升高,糖尿病并发症的发生率也随之升高(P<0.01)。结论:糖化血红蛋白检测对糖尿病患者诊断、血糖控制及疗效评价具有重要的临床意义,是观察糖尿病病情的一个较稳定指标。
Objective:To investigate the diagnostic value of glycosylated hemoglobin (HbAlc) detection in clinical trials ofdiabetes mellitus.Methods:90 patients with diabetes were selected as the observation group,at the same time,90 healthy personwho took medical examination were served as control group.In the two groups, HbA1c and fasting blood glucose(FBG)weremeasured by the method of immune transmission turbidity method and glucose oxidase method respectively.We compared thecorrelation between HbAlc and the fasting blood glucose level and the incidence of diabetes complications.Results:The fastingblood glucose and HbAlc in the diabetes group were significantly higher than those in the healthy control group.With the elevatedof HbAlc level,the incidence of complications of diabetes mellitus also increased(P<0.01).Conclusion:Glycosylated hemoglobindetection has important clinical significance for the diagnosis,blood glucose control and efficacy evaluation in patients withdiabetes,and it is a relatively stable indicator of diabetes mellitus.
作者
李顺群
Li Shunqun(Department of Laboratory,Concorde Orthopaedic Hospital of Zhoukou City,Henan Province 466000)
出处
《中国社区医师》
2016年第6期150-150,152,共2页
Chinese Community Doctors
关键词
糖化血红蛋白
诊断
意义
Glycosylated hemoglobin
Diagnosis
Significance
