摘要
目的:总结肝硬化门脉高压消化道出血的治疗经验。方法:收治肝硬化门脉高压消化道出血患者80例,分两组,各40例。对照组给予卧床休息,禁食,给予垂体后叶素注射液0.2 U/min微量泵维持3 d,泮托拉唑注射液40mg+250 m L生理盐水静脉滴注,1次/d,连续治疗5 d。观察组给予卧床休息,禁食,善宁0.1 mg+20 m L生理盐水缓慢静脉注射,尔后微量泵持续静脉泵入,25μg/h,连续治疗3 d,泮托拉唑注射液40 mg+250 m L生理盐水静脉滴注,1次/d,连续治疗5 d。结果:观察组有效率95.0%,高于对照组的80.0%(P<0.05);观察组出现不良反应发生率5.0%,低于对照组的17.5%(P<0.05)。结论:善宁联合泮托拉唑治疗肝硬化门脉高压合并上消化道出血止血快,不良反应少。
Objective:To sum up the experience in the treatment of liver cirrhosis with portal hypertension.Methods:80 patients with liver cirrhosis with portal hypertension were selected.They were divided into two groups,40 cases in each.Patients in the control group were treated with bed rest,fasting, posterior pituitrin injection 0.2 U/min micro pump maintain 3 d,pantoprazole injection 40 mg+250 mL normal saline intravenous infusion,1 times/d for 5 d.Patients in observation group were treated with bed rest and fasting,octreotide 0.1 mg + 20 mL NS slow intravenous injection,later trace pump continuous infusion into,25 μ g/h,continuous treatment 3 d,pantoprazole injection 40 mg+250 mL normal saline intravenous infusion,1 time/d for 5 d.Results:The effective rate of the observation group was 95.0% higher than that of the control group of 80.0%(P<0.05).The incidence rate of adverse reaction was 5.0% lower than that of the control group of 17.5% (P<0.05).Conclusion:Sandostatin combined with pantoprazole in treatment of cirrhotic portal hypertension with upper gastrointestinal bleeding can stop bleeding quickly,with less adverse reactions.
作者
代贵学
Dai Guixue(Department of Internal Medicine,the Third People's Hospital of Sanmenxia City,Henan Province 472143)
出处
《中国社区医师》
2016年第10期34-34,36,共2页
Chinese Community Doctors
关键词
肝硬化门静脉高压
消化道出血
善宁
泮托拉唑
Portal hypertension
Gastrointestinal bleeding
Sandostatin
Pantoprazole
