摘要
目的:探讨血清降钙素水平(PCT)对神经内科ICU重症患者抗感染治疗的指导价值。方法:收治重症感染患者110例,随机分为对照组与观察组,对照组行常规抗生素治疗,在观察组,血清PCT<0.25μg/L者采用非抗生素治疗,血清PCT≥0.25μg/L者采用抗生素治疗,比较两组治疗效果。结果:在观察组,死亡率5.45%,明显低于对照组的12.73%,抗生素使用时间与住院时间明显短于对照组(P<0.05)。两组治疗后的CRP及WBC计数均明显降低(P<0.05),但组间比较,差异无统计学意义(P>0.05)。观察组治疗后的PCT水平明显低于治疗前(P<0.05)。结论:PCT为ICU重症感染患者重要评价指标,对抗生素的使用具有重要的指导意义。
Objective:To explore the clinical value of serum procalcitonin(PCT) in the guidance of anti infection treatment ofsevere patients in ICU of department of internal medicine.Methods:110 patients with severe infection were selected.They wererandomly divided into the control group and the observation group.The control group was given routine antibiotic therapy.In theobservation group,the patients with serum PCT less than 0.25 μ g/L were given non antibiotic treatment,and the patients withserum PCT more than 0.25 μg/L were given antibiotic treatment.We compared the treatment effects of two groups.Results:In theobservation group,the mortality rate of 5.45% was significantly lower than 12.73% of the control group,and the use time ofantibiotics and hospitalization time were significantly shorter than the control group(P<0.05).After treatment,the CRP and WBCcount of the two groups were significantly reduced(P<0.05),but there was no significant difference between the groups(P>0.05).In the observation group,the level of PCT after treatment was significantly lower than that before treatment(P<0.05).Conclusion:PCT was an important evaluation index for infection situation of severe patients in ICU,and it had important guiding significancefor the use of antibiotics.
作者
董俊林
Dong Junlin(Department of Internal Medicine,the People's Hospital of Wusu City,Xinjiang 833000)
出处
《中国社区医师》
2016年第21期134-134,136,共2页
Chinese Community Doctors
关键词
血清降钙素原
神经内科
重症感染
Serum calcitonin
Department of internal medicine
Severe infection
