摘要
目的:探讨卡维地洛治疗慢性充血性心衰的临床疗效及用药安全性。方法:104例慢性充血性心力衰竭患者按照就诊顺序随机分为两组,每组52例。对照组给予常规抗心衰治疗,观察组在对照组的治疗基础上加用卡维地洛,对比两组临床治疗效果及用药安全性。结果:观察组总有效率高于对照组(P<0.05)。观察组治疗后LVEF、LVEDD和LVESD较治疗前和对照组均有明显改善(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:卡维地洛治疗慢性充血性心衰疗效显著,能够有效改善患者的心功能,安全性高。
Objective:To explore the clinical curative effect and medication safety of carvedilol in the treatment of chroniccongestive heart failure.Methods:In accordance with the order of treatment,104 patients with chronic congestive heart failure wererandomly divided into two groups with 52 cases in each.The control group was given routine anti heart failure treatment.Theobservation group was given carvedilol on the basis of the treatment of the control group.The clinical curative effect andmedication safety were compared between groups.Results:The total effective rate of the observation group was significantly higherthan that of the control group(P<0.05).The posttreatment LVEF、LVEDD and LVESD of the observation group were significantlyimproved than those before treatment and the control group(P<0.05).There was no significant difference in the incidence rates ofadverse reactions between groups(P>0.05).Conclusion:Carvedilol in the treatment of chronic congestive heart failure has asignificant curative effect.It can effectively improve the heart function of patients,and its safety is high.
作者
刘凤梅
Liu Fengmei(Department of Internal Medicine,Zhengzhou Ersha Hospital 450000)
出处
《中国社区医师》
2016年第21期21-22,共2页
Chinese Community Doctors
关键词
慢性充血性心衰
卡维地洛
临床疗效
安全性
Chronic congestive heart failure
Carvedilol
Clinical curative effect
Safety
