摘要
目的探讨社区综合干预对高脂血症患者的治疗效果。方法选取2014年4月3日~4月24日在北京市西城区广内社区卫生服务中心体检的270例高脂血症患者,其中男性175例,女性95例,年龄为37~78岁,平均年龄(51.1±7.1)岁。随机分为干预组与对照组,每组135例。对照组患者给予常规药物进行降脂治疗,观察组在对照组的基础上进行社区综合干预。治疗6个月后,对两组患者的服药依从性、体质指数(BMI)、腰臀比(WHR)和三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)进行比较和分析。结果干预组中按时服药的患者占91.1%,显著优于对照组(77.0%),差异具有统计学意义(P<0.05)。治疗后干预组的体重指数(BMI)和腰臀比(WHR)分别为(24.1±3.1)kg/m^2和(0.77±0.09),均显著小于对照组[(25.6±3.6)kg/m^2和(0.82±0.11)],差异具有统计学意义(P均<0.05);治疗后干预组的TG、TC和LDL-C值分别为(1.58±0.33)mmol/L、(5.13±1.08)mmol/L和(3.22±1.17)mmol/L,显著低于对照组[(1.73±0.38)mmol/L、(5.41±1.13)mmol/L和(3.53±1.25)mmol/L],差异均具有统计学意义(P均<0.05);而HDL-C值为(1.19±0.33)mmol/L,显著高于对照组(1.08±0.31)mmol/L,差异具有统计学意义(P<0.05)。结论社区综合干预治疗高脂血症疗效显著,值得临床推广。
Objective To discuss the curative effect of community comprehensive intervention in patients withhyperlipidemia. Methods The patients with hyperlipidemia (n=270, male 175, female 95, aged from 37 to 78 andaverage age+51.1±7.1) were chosen from Apr. 3, 2014 to Apr. 24, 2014, and randomly divided into interventiongroup and control group (each n=135). The control group was given routine drugs for reducing blood fat, andintervention group was additionally given community comprehensive intervention. After treatment for 6 m, thechanges of drug compliance, body mass index (BMI), waist-hip ratio (WHR), triglyceride (TG), total cholesterol (TC),high-density lipoprotein-cholesterol (HDL-C) and low-density lipoprotein-cholesterol (LDL-C) were comparedand analyzed in 2 groups. Results The percentage of patients taken drugs on time was 91.1% in intervention groupand 77.0% in control group (P<0.05). BMI was (24.1±3.1) kg/m2 and WHR was (0.77±0.09) in interventiongroup, and (25.6±3.6) kg/m2 and (0.82±0.11) in control group (all P<0.05). TG was (1.58±0.33) mmol/L, TCwas (5.13±1.08) mmol/L and LDL-C was (3.22±1.17) mmol/L in intervention group, and TG was (1.73±0.38)mmol/L, TC was (5.41±1.13) mmol/L LDL-C was (3.53±1.25) mmol/L in control group (all P<0.05). HDL-Cwas significantly higher in intervention group (1.19±0.33) mmol/L than that in control group (1.08±0.31) mmol/L(P<0.05). Conclusion The curative effect of community comprehensive intervention is significant, which is worthto be popularized in clinic practice.
作者
张晴
ZHANG Qing(General Department, Community Health Service Center, Guang'anmennei Community, Xicheng District, Beijing 100053, China)
出处
《中国循证心血管医学杂志》
2016年第4期494-496,共3页
Chinese Journal of Evidence-Based Cardiovascular Medicine
关键词
社区综合干预
高脂血症
疗效
Community comprehensive intervention
Hyperlipidemia
Curative effect
