摘要
目的 探讨血浆渗透压测定在临床脑卒中治疗中的价值和意义。方法 对 2 11例脑卒中患者进行了入院血浆渗透压测定 ,其中 35例在第 1周进行了动态监测。结果 住院期间死亡者入院血浆渗透压水平 (30 5 .6 6± 13.4 5mOsm/kg .H2 O)高于存活者 (2 92 .0 1± 9.0 0mOsm/kg·H2 O) ,入院血浆渗透压是影响住院病死率的独立危险因素 (OR =7.75 ,95 %CI 3.2 2～ 16 .90 ) ,其水平与脑卒中类型 (出血或缺血 )无关 ,与病变程度有关。动态监测显示血浆渗透压与甘露醇用量有关。结论 血浆渗透压是评价急性脑卒中预后并指导治疗的可靠指标之一。
Objective To evaluate the role of plasma osmolality measurement in acute stroke patients.Methods The plasma osmolality were measured in 211 acute stroke patients at admission, and 35 cases of them were monitored dynamically during the first week.Results Plasma osmolality was significantly higher in those who died compared with survivors, The patients whose plasma osmolality over 296 mOsm/kg.H 2O at admission were significantly associated with in hospital mortality(OR= 7.75 , 95% CI 3.22 ～ 16.90 ) Plasma osmolality wasn't associated with the stroke types (ischemic or hemorrhagic), but was related with the stroke severity. The dynamic monitoring showed that plasma osmolality was associated with the used mannitol dosage.Conclusion Plasma osmolality measurement plays an important role in predicting outcome and directing dehydration treatment in acute stroke patients.
出处
《卒中与神经疾病》
2002年第5期273-276,共4页
Stroke and Nervous Diseases
关键词
血浆渗透压
脑卒中
病死率
Plasma osmolality Acute stroke Mortality
