摘要
目的 研究肝脏局灶病变的血供对病灶表观扩散系数 (apparentdiffusioncoefficient,ADC)的影响。方法 研究对象包括 87例病人 ,共 1 59个肝脏局灶病变 ,采用不同的b值和b值差的扩散加权成像 (diffusion weightedimaging,DWI)技术对各病灶及肝脏、脾脏及胆囊进行ADC值的测量。结果小b值和b值差所检测到的ADC值受组织或病变内血流灌注的影响 ,海绵状血管瘤的平均ADC值最高 (7 64× 1 0 - 3mm2 /s) ,富血供恶性肿瘤的平均ADC值明显高于乏血供恶性肿瘤 (分别为 3 47×1 0 - 3mm2 /s和 2 39× 1 0 - 3mm2 /s,t=2 39,P <0 0 1 ) ,肝囊肿的ADC值几乎不受b值和b值差的影响。结论 当利用小b值和小b值差进行DWI时 ,组织或病变的ADC值受血流灌注的影响较大。
Objective To investigate the affection of lesion blood supply on apparent diffusion coefficient (ADC) of focal hepatic mass Methods Diffusion weighted imaging (DWI) with different b values was performed in 87 patients with 159 focal hepatic lesions ADCs of lesion, liver, spleen, gallbladder were measured in every case Results On DWI with small b value and small b value remainder, ADCs were affected by blood perfusion of tissues or lesions The mean ADC of hypervascular lesions was significantly higher than that of hypovascular lesions on DWI with small b value, and hemoangiomas got the highest mean ADC The mean ADC of hepatic cysts was not affected by b value Conclusion Blood perfusion affects ADC of tissue or focal hepatic lesion, particularly on DWI with small b value, and to some degree, DWI and ADC can reflect the blood supply of focal hepatic lesion
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2002年第10期892-895,共4页
Chinese Journal of Radiology
