摘要
目的:观察恶性心包积液心包穿刺置管引流并实施腔内化疗的疗效及安全性。方法:在48例恶性心包积液中,19例有心包填塞症状者行心包穿刺置管并腔内化疗。29例无心包填塞症状未行腔内治疗的恶性心包积液患者均接受了全身化疗。结果:腔内化疗完全缓解9例,好转8例,无效1例,有效率89.5%。未行腔内化疗的恶性心包积液患者接受了全身化疗,有效率34.5%。结论:在心包积液量较大时,应首选腔内注药治疗,安全有效,不良反应小。
Objective:The aim of this study was to approach an efficient way in t he treat-ment of pericardial effusion due to advanced cancer.Methods:In forty-eight patients with peri-cardial effusion of advanced cancer,nineteen patie nts were catheterized and drained after pericar-diocentesis,then cisplatin,mi tomycin C,methotrexatum and dexamethasone were injected into the pericardial ca vity for intrapericardial chemotherapy.Another twenty-nine patients accepted chemotherapy.Results:The total effective rate was89.9%with9cases of comp lete respones and8cases of partial response in19patients.In29patients with chemotherapy the total ef-fective rate was34.5%.Conclusion:With severe pericardial effusion,the drain and injecting anticarcinogens into pericardial c avity may be a better way to control malignant pericardial effu-sion of advanc ed cancer.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2002年第9期633-635,共3页
Chinese Journal of Clinical Oncology
关键词
恶性心包积液
心包穿刺术
腔内化疗
晚期肿瘤
并发症
Malignant pericardial effusion Pericardiocentesis Intrape ricardial chemotherapy
