摘要
目的 分析 4 2例白血病患者化疗前后血清中 SIL - 2 R和 SA含量的变化。方法 分别应用酶联法和化学法测定 4 2例白血病患者化疗前后血清中 SIL- 2 R和 SA的含量 ,同时与 35名正常健康人作对照。结果 化疗前血清中 SIL - 2 R和 SA含量均显著地高于正常人组 (P<0 .0 1) ,化疗后一个月均有的降低 (P<0 .0 5 ) ,化疗后 6个月复发者血清 SIL - 2 R和 SA持续异常 ,未复发者 SIL - 2 R和 SA恢复正常。结论 检测白血病患者血清中 SIL -2 R和 SA含量的变化可作为患者的免疫功能的监测指标之一 。
Objective To analyze the changes of the levels of SIL 2R and SA before and after chemotherapy in 42 patients with leukemia.Methods Levels of serum SIL 2R and SA in 42 cases before and after chemotherapy of leukemia and 35 normal controls were detected by ELISA and biochemisty.Results Pre chemotherapy SIL 2R and SA levels in the patients were higher than those in controls( P <0.01).One month after chemotherapy SIL 2R and SA levels were decreased( P <0.05).The levels of SIL 2R and SA were higher in the patients with recurrence 6 months post chemotherapy,the SIL 2R and SA levels returned to normal in the patients without recurrence.Conclusion Detection of serum levels of SIL 2R and SA might be a useful method of monitoring the immune function in patients with leukemia.
出处
《淮海医药》
2002年第6期465-466,共2页
Journal of Huaihai Medicine
