摘要
目的 探讨矽肺以及矽肺结核患者血液黏度和体外血栓的变化。方法 检测 2 88例矽肺患者、178例矽肺结核患者以及 15 0例健康对照者血液黏度和体外血栓的长度和干重。结果 矽肺组和矽肺结核组与正常对照组比较血液黏度 (Ⅰ期矽肺除外 )和体外血栓均显著增高 ,患者各组内Ⅰ、Ⅱ及Ⅲ期间血液黏度亦随期别增加而递增 ,且差异显著 ,体外血栓无显著差异 ;Ⅰ、Ⅱ期矽肺结核患者分别与同期矽肺患者比较 ,全血黏度在高、中剪切率下显著增加 ,在低剪切率下以及血浆黏度差异无显著性 ,体外血栓长度和干重亦增加显著 ;Ⅲ期矽肺结核患者与Ⅲ期矽肺患者比较 ,血液黏度和体外血栓均无显著差异。结论 矽肺患者血液呈高黏、高凝状态 ,且随期别增加血液黏度和体外血栓长度及干重均相应增加 ,合并结核者尤甚。
Objective To explore the changes of blood viscosity and external thrombus in patients with silicosis and silicosis complicated with tuberculosis (TB) Method Blood viscosity and external thrombus were measured in 288 patients with silicosis, 178 patients with silicosis complicated by TB and 150 healthy subjects Results Blood viscosity and external thrombus value were significantly higher in the patients of silicosis and silicosis complicated with TB than in the healthy controls, except for patients of phaseⅠof silicosis Blood viscosity in the silicotics increased significantly with the advance of the disease, but no significant difference in external thrombus between patients in different phases Apparent viscosity of whole blood significantly increased in the high shear rate (200 s -1 ) and middle shear rate (30 s -1 ) in patients of silicosis complicated with TB than in those without complication of TB at the same phases, but not seen in the low shear rate (5 s -1 ) and in plasma viscosity, and the length and dried weight of external thrombus increased significantly too There was no significant difference in blood viscosity and external thrombus between patients of silicosis at phase Ⅲ and those of silicosis complicated with TB at the same phase Conclusion Blood in patients with silicosis appeared highly viscose and highly coagulant status Blood viscosity and external thrombus value significantly increased with the advance of the disease, especially in the patients complicated with TB
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2002年第5期330-331,共2页
Chinese Journal of Preventive Medicine
关键词
矽肺
矽肺结核
血液黏度
血栓形成
诊断
Silicosis
Silicotuberculosis
Blood viscosity
Thrombosis
