摘要
目的 :探讨不明原因反复自然流产 (RSA)患者在不同时期血清sIL - 2R水平。方法 :采用双抗体夹心ELISA法测定了 2 6例非孕期RSA患者 ,2 2例孕期RSA患者 ,8例出现先兆流产的孕期RSA患者 ,2 0例正常妊娠的孕妇与2 1例正常经产妇血清中sIL - 2R水平。结果 :出现先兆流产组血清sIL - 2R水平显著高于其它组 (P <0 .0 1) ,其余 4组间无显著性差异 (P >0 .0 5 )。结论 :血清sIL - 2R水平升高与先兆流产有关 ,RSA患者孕期血清sIL - 2R水平升高应警惕再次发生流产的可能。
Objective: To investigate the change and significance of serum soluble interlenkin 2 receptor (sIL-2R) levels in women with undefined recurrent spontaneous abortion(RSA).Methods: sIL-2R in the serum was measured by ELISA in non-pregnant RSA patients(n=26),pregnant RSA patients (n=22),pregnant RSA patients with threatened absortion (n=8),normal pregnant women (n=20),and women having histories of normal pregancy (n=21).Results: The level of sIL-2R in the group of pregnant RSA patients with threatened absortion was significantly higher than that of the others ( P <0.01).No significant difference was found among the other four groups( P >0.05).Conclusion: The increase of sIL-2R may be associated with threatened absortion.It is necessary to be on alert for abortion while the level of sIL-2R in the serum of pregnant RSA women is high.
