摘要
目的 :比较术前治疗方式对Ⅱb期宫颈癌疗效的影响。方法 :4 8例手术治疗的Ⅱb期宫颈癌 ,根据术前辅助治疗方法 ,采用回顾性分析 ,分为术前介入组和术前后装组 ,比较两组的近期疗效 ,盆腔淋巴结转移和生存率。结果 :术前介入组局部肿瘤消退明显 ,近期有效率为 92 % ,较术前后装组的 4 3%明显提高 (χ2 =6 .74 ,P <0 .0 5 ) ;淋巴结转移率 2 0 % ,明显低于术前后装组的 5 2 % (χ2 =5 .4 2 ,P <0 .0 5 ) ;3年生存率 84 % ,明显高于术前后装组的 5 2 % (χ2 =5 .6 4 ,P <0 .0 5 )。结论 :介入化疗是治疗Ⅱb期宫颈癌有效的术前辅助治疗手段 ,能有效控制局部肿瘤 ,减少淋巴转移 ,提高生存率。
Objective: To compare the effect of preoperative treatment modality on cervical carcinoma in stage Ⅱb. Methods: 48 patients with FIGO stage Ⅱb cervical cancer were divided into two groups according to preoperative treatment. There are 25 patients with intraarterial chemotherapy (Group1) and 23 patients with radiotherapy (Group2) before operation. Short-term effect, lymphnode metastasis, and survival rate were analysed. Results: The short-term response rate with group 1 and group 2 were 92% and 43%, group 1 was significantly higher than that in group 2( χ 2 =6.74,P <0.05);the rate of lymphnode metastasis in group1 was 20%, and it was significantly lower than that in group 2(52%), (χ 2 =5.42, P <0.05);the three-year survival rate was 84%, and it was significantly higher than that in group 2 (52%), ( χ 2 =5.64,P <0.05). Conclusion: Preoperative intraarterial chemotherapy is effective to cervical carcinoma in stageⅡb, it can shrink tumor size, decrease the lymphnode metastasis rate, and elevate survival rate.
出处
《中国临床医学》
2002年第4期426-427,共2页
Chinese Journal of Clinical Medicine
关键词
介入化疗
宫颈癌
放射疗法
Intraarterial chemotherapy Cervical cancer Radiotherapy
