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辛伐他汀联合缬沙坦治疗糖尿病肾病的临床观察

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摘要 目的:探讨辛伐他汀联合缬沙坦治疗糖尿病肾病(DN)的疗效及机制。方法:选择糖尿病肾病160例,随机分为治疗组和对照组各80例,对照组单用缬沙坦治疗,治疗组应用缬沙坦联合辛伐他汀治疗,疗程8w。治疗前后观察血脂(TG、TC)、尿白蛋白排泄率(UAER)及血肌酐(Scr)的变化。结果:各组较治疗前下降,治疗组下降优于对照组,差异有统计学意义(P<0.05)。结论:采用辛伐他汀联合缬沙坦治疗糖尿病肾病具有降血脂、减少尿蛋白排泄、改善肾功能、延缓病情进展的作用。
作者 张俊生
出处 《临床医药实践》 2010年第7X期946-947,共2页 Proceeding of Clinical Medicine
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