期刊文献+

干扰素联合双环醇片治疗慢性乙型肝炎60例

下载PDF
导出
摘要 目的:了解干扰素联合双环醇片治疗e抗原阳性慢性乙型肝炎的疗效。方法:采用随机分组,干扰素联合双环醇片治疗e抗原阳性慢性乙型肝炎60例,与干扰素治疗组48例作对照。结果:联合治疗组与对照组ALT复常率第1个月后分别为25%和20.8%,差异无统计学意义(P>0.05);第2、3、6个月后联合治疗组ALT复常率分别为73.3%、90%和96.7%,均高于对照组50%、72.9%和83.3%(P<0.05);联合治疗组第3、6个月后HBeAg阴转率、抗HBe阳转率、HBV-DNA阴转率分别为40%、53.3%、26.7%、43.3%和46.7%、68.3%;均高于对照组的20.8%、33.3%、8.3%、25%和27.1%、47.9%,差异有统计学意义(P<0.05)。结论:干扰素联合双环醇片能提高慢性乙型肝炎的疗效。
出处 《临床医药实践》 2009年第10X期755-756,共2页 Proceeding of Clinical Medicine
  • 相关文献

参考文献5

二级参考文献24

  • 1蔡雄,王国俊,瞿瑶,樊成辉,张瑞祺,徐文胜.苦参素注射液治疗慢性乙型肝炎临床疗效分析[J].第二军医大学学报,1997,18(1):47-49. 被引量:345
  • 2Liu GT, Zhang CZ, Li Y, et al. Clinical and pharmacological study of Bicyclol, a potential anti-chronic viral hepatitis drug. Chin Med Sci J, 1999,14:51-53. 被引量:1
  • 3Janssen HL,Gerken G,Carreno V,et al.Interferon alfa for chronic hepatitis B infection:increased efficacy of prolonged treatment.The European Concerted Action on Viral Hepatitis.Hepatology,1999,30:238-243. 被引量:1
  • 4Craxi A,Di Bona D,Camma C.Interferon-alpha for HBeAg-positive chronic hepatitis B.J Hepatol,2003,39(Suppl 1):S99-105. 被引量:1
  • 5Cooksley WG,Piratvisuth T,Lee SD,et al.Peginterferon α-2a (40kDa):an advance in the treatment of hepatitis B e antigen-positive chronic hepatitis B.J Virol Hepatitis,2003,10:298-305. 被引量:1
  • 6Marcellin P,Lau GKK,Bonino F,et al.Peginterferon alfa-2a alone,lamivudine alone and the two in combination in patients with HbeAg-negative chronic hepatitis B.N Engl J Med,2004,351:32-43. 被引量:1
  • 7Janssen HL,van Zonneveld M,Senturk H,et al.Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-postive chronic hepatitis B:a randomized trial.Lancet,2005,365:123-129. 被引量:1
  • 8Chan HL,Leung NW,Hui AY,et al.A randomized,controlled trial of combination therapy for chronic hepatitis B:comparing pegylated interferon-alpha2b and lamivudine with lamivudine alone.Ann Intern Med,2005,142(4):240-250. 被引量:1
  • 9Lok AS,Lai CL,Leung N,et al..Long-term safety of lamivudine treatment in patients with chronic hepatitis B.Gastroenterology,2003,125:1714-1722. 被引量:1
  • 10Marcellin P,Chang TT,Lim SG,et al.Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B.N Engl J Med,2003,348(9):808-816. 被引量:1

共引文献41

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部