摘要
目的:了解创口净对常见菌的抗菌作用。方法:测定创口净在体外破伤风梭菌、产气夹膜梭菌,绿脓杆菌、金黄色葡萄球菌、大肠杆菌的抑菌试验,并与常用消毒剂比较分析。结果:创口净对破伤风梭菌和产气夹膜梭菌的最小抑菌浓度与大肠杆菌均为1.6μg·ml-1,对金黄色葡萄球菌的最小抑菌浓度为0.78μg·ml-1,而绿脓杆菌为12.5μg·ml-1;创口净在2.5min就能杀灭绝大多数细菌,而75%乙醇、0.1%新洁尔灭、0.05%洗必泰所需时间更长。结论:创口净可有效地杀灭常见致病性厌氧菌和非厌氧菌,为一种高效、快速的广谱抗菌剂,可用于各种创伤感染的预防和治疗。
<Abstrcat>Objective:To investigate the inhibition of Chuang Kou Jing (CKJ)against general infectious bacteria.Methods:To analyse the inhibition of CKJ against the bacteria such as Clostridium perfringens, Clostridiumtetani,Staphyloccus aureus, Escherichia coli in vitro and compared with other disinfections.Results:The minimal inhibitory concentration (MIC) of CKJ for C. Perfringens, C. tetani and E. Coli were all 1.6 μg·ml-1. The MIC for S. aureus and P. Auruginosa were 0.78 μg·ml-1 and 12.5 μg·ml-1 respectively. It took 2.5 min for CKJ to kill most of the bacteria, but it took more time for 75% alcohol, 0.1 % bromogeramine, and 0.05% Chlohexidine.Conclusion:CKJ can efficiently inhibit or kill the general anaerobic and aerobic bacteria, it is a high effective, speed antibacterial agent, and can be used to treat and prevent various traumatic wound infection.
出处
《西北国防医学杂志》
CAS
2002年第5期337-339,共3页
Medical Journal of National Defending Forces in Northwest China
基金
.NULL.
关键词
创口净
抗菌作用
体外研究
厌氧菌
非厌氧菌
外用药
Medical bacteriology
Chuang Kou Jing
antibacterial effect
anaerobic bacteria
aerobic bacteria
