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不同的C-反应蛋白测定方法比较及其对于心血管风险评估的作用

Comparison of differing C-reactive protein assay methods and their impact on cardiovascular risk assessment
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摘要 A medium-sensitivity assay for C-reactive protein(CRP)was compared with a high-sensitivity, enhanced immunoturbidimetric assay in 803 angiographically studied patients. Different absolute CRP values were found by the assays, but there was a high correlation by quartile rank and similar predictive values for death and myocardial infarction. This suggests that the conclusions of previous studies performed using the medium sensitivity assay are still valid but that cross-study comparisons should use percentile rank. A medium-sensitivity assay for C-reactive protein(CRP)was compared with a high-sensitivity, enhanced immunoturbidimetric assay in 803 angiographically studied patients. Different absolute CRP values were found by the assays, but there was a high correlation by quartile rank and similar predictive values for death and myocardial infarction. This suggests that the conclusions of previous studies performed using the medium sensitivity assay are still valid but that cross-study comparisons should use percentile rank.
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