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对低血流供应眼施行小切口白内障手术的益处 被引量:4

Beneficial effects of small-incision cataract surgery in patients demonstrating reduced ocular blood flow characteristics
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摘要 Purpose: To investigate intraocular pressure (IOP) and ocular haemodynamics fo llowing small incision cataract surgery. Methods: Systemic and ocular haemodynam ics, and IOP, were measured pre-operatively and 1 month post-operatively, in 2 5 eyes of 25 patients (mean age 72.6±7.9 years) scheduled for small incision ca taract surgery and intraocular lens implantation; these values were compared to an untreated age-matched healthy group (n=25, mean age 72.3±5.0 years). For ea ch eye, the Ocular Blood Flow Analyser (OBFA, Paradigm Inc., UT, USA) was used t o obtain measurements of IOP, pulsatile ocular blood flow (POBF), pulse volume ( PV), ocular pulse amplitude (PA), and pulse rate (PR). Systemic blood pressure m easurements were obtained at each visit. Pre-and post-operative values for the cataract group were compared using repeated measures analysis of variance, and compared to the normal group using analysis of variance. Results: Pre-operative ly, IOP was significantly higher in the cataract group compared to the age-matc hed normal control group (P < 0.001). Cataract surgery resulted in a significant 16.7%reduction in IOP (P=0.001). Consequently, the post-operative IOP in the cataract group was similar to that of the normal group (P > 0.05). Both pre-and post-operative POBF and PV values for the cataract groupwere significantly low er than for the normal age-matched group (P < 0.0125). Small incision cataract surgery led to an 8.3%post-operative increase in POBF (P=0.0118) and 15.5%inc rease in PV (P < 0.001). No changes in PA or PR were evident. Conclusion: These data suggest that cataract patients exhibit higher IOP and reduced ocular perfus ion characteristics compared to an age-matched normal healthy group. Following cataract surgery, IOP reduced and ocular pulsatility improved. Purpose: To investigate intraocular pressure (IOP) and ocular haemodynamics fo llowing small incision cataract surgery. Methods: Systemic and ocular haemodynam ics, and IOP, were measured pre-operatively and 1 month post-operatively, in 2 5 eyes of 25 patients (mean age 72.6±7.9 years) scheduled for small incision ca taract surgery and intraocular lens implantation; these values were compared to an untreated age-matched healthy group (n=25, mean age 72.3±5.0 years). For ea ch eye, the Ocular Blood Flow Analyser (OBFA, Paradigm Inc., UT, USA) was used t o obtain measurements of IOP, pulsatile ocular blood flow (POBF), pulse volume ( PV), ocular pulse amplitude (PA), and pulse rate (PR). Systemic blood pressure m easurements were obtained at each visit. Pre-and post-operative values for the cataract group were compared using repeated measures analysis of variance, and compared to the normal group using analysis of variance. Results: Pre-operative ly, IOP was significantly higher in the cataract group compared to the age-matc hed normal control group (P < 0.001). Cataract surgery resulted in a significant 16.7%reduction in IOP (P=0.001). Consequently, the post-operative IOP in the cataract group was similar to that of the normal group (P > 0.05). Both pre-and post-operative POBF and PV values for the cataract groupwere significantly low er than for the normal age-matched group (P < 0.0125). Small incision cataract surgery led to an 8.3%post-operative increase in POBF (P=0.0118) and 15.5%inc rease in PV (P < 0.001). No changes in PA or PR were evident. Conclusion: These data suggest that cataract patients exhibit higher IOP and reduced ocular perfus ion characteristics compared to an age-matched normal healthy group. Following cataract surgery, IOP reduced and ocular pulsatility improved.
出处 《世界核心医学期刊文摘(眼科学分册)》 2005年第10期30-31,共2页 Digest of the World Core Medical Journals:Ophthalmology
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