期刊文献+

海口市吸毒人群TT病毒与肝炎病毒感染状况的调查 被引量:2

INVESTIGATION ON TT VIRUS AND HEPATITIS VIRUS INFECTION AMONG DRUG USERS IN HAIKOU.
下载PDF
导出
摘要 目的 :研究海口市吸毒人群病毒与甲~庚型肝炎病毒感染状况。方法 :对 2 2 1例吸毒者进行不同因素分析 ,采用巢式 PCR法检测血清中的 TTV DNA,对一株 TTV部分基因序列进行了测定 ;用 EL ISA法检测甲~庚型肝炎病毒。结果 :2 2 1名吸毒人群中 TTV DNA与甲~庚型肝炎病毒感染率分别为 HBV45 .7%、 TTV DNA31.6 %、 HCV11.8%、HGV10 .4%、 HEV2 .2 %、HAV0 .4% ;静脉毒瘾者、有非固定婚外性伴侣等因素与 TTV、HBV、HCV感染有关 ;TTV与甲~庚型肝炎病毒均存在合并感染 ;一株 TTV DNA序列与 Gen Bank中主要序列核苷酸同源性大于 98%。结论 :吸毒人群是 TTV和肝炎病毒感染的高危人群 ,静脉毒瘾者、有非固定性伴侣是 TTV、HBV、HCV传播的重要因素 ,TTV还存在非血源性传播途径 。 Objevtive:To investigate TT virus and hepatitis A to G virus infection among drug users in Haikou.Methods:TTV DNA in serum samples was detected by nested polymeras chain reaction,partial genes of one strain of TTV was cloned and sequerced,and their genetiv variation was analyzed.Hepatitis A to G was detected by ELISA.Results:The positive rate of HBV(45 7%)、TTV DNA(31 6%)、HCV(11 8%)、HGV(10 4%)、HEV(2 2%)、HAV(0 4%) was detected among 221 drug users.The sequence analysis show that there were above 98% nucleotide identity among GenBank.Conclusion:The intravenous drug users are the population at high risk for TTV and hepatitis infection.The intravenous drug users and people who have unsteady sex companion are the main transmission factors for TTV、HBV、HCV.TTV may be transmitted by non blood transfusion routes.
出处 《现代预防医学》 CAS 2000年第3期315-317,共3页 Modern Preventive Medicine
基金 海南省基础性研究项目!(8990 6 )
关键词 海口市 调查 吸毒人群 TT病毒 肝炎病毒 聚合酶链反应 Druy addicts TT virus Hepatitis virus Polymerase chain reaction
  • 相关文献

参考文献4

  • 1吴尊友,张家鹏,段松,程何何,李志荣,董勒弄,贾曼红,黄素芬,毕秀琼,赵忠林,李文可,马宗江,Roger Detels.云南省某县男性青年吸毒现象调查[J].中华预防医学杂志,1996,30(6):327-329. 被引量:12
  • 2NishizawaT,CkamotoH,KonishiK,etal.AnovelDNAvirus(TTV)associatedwithelevatedtransminaselevelsinposttransfusionnepatitsofunknwonetiology[J].BiochemBiophysResCommun,1997,241:92-97. 被引量:1
  • 3OKamotoH,NishizawaT,KatoN,etal.MolecularcloningandcharacterizationofanovelDNAvirus(TTV)associatedwithposttransfusionhepatitisofunknwonetiology[J].HepatolRes,1998,10:1-16. 被引量:1
  • 4CharlyonM,AoljeiP,PotenuchaJ,etal.TT-virusinfectioninNorthAmericanblooddonors,patientswithfulminanthepaticfailure,andcrypiogeniccirrhosis[J].Heapatology,1998,28:839-842. [ 被引量:1

二级参考文献2

共引文献11

同被引文献15

  • 1王丽荣,陈嘉琳,陈益,李升华,何紫电,杨春,符立龙,叶国强,柯建义.吸毒人群HBV、HCV感染状况及吸毒合并两种病毒感染对ALT异常的影响[J].中国误诊学杂志,2004,4(5):675-677. 被引量:6
  • 2Leary TP,Muerhoff AS,Simons JN,et al. Sequence and genomic organization of GBV-C:a novel member of the Flaviridate associated with human non A-E hepatitis[J]. J Med Virol,1995,48:60-67. 被引量:1
  • 3Villari P,Ribera G,Nobile CG,et al. Antibodies to the E2 protein of GB virus C/hepatitis G virus:prevalence and risk factors in different populations in Italy[J]. Infection,2001,29(1 ):17-23. 被引量:1
  • 4Hyland CA,Mison L,Solomon N,et al. Exposure to GB virus type C or hepatitis G virus in selected Australian adult and children populations[J]. Transfusion, 1998 ,38(9) :821-827. 被引量:1
  • 5Stark K, Detection of the hepatitis G Virus Genome among injecting drug users,homosexual and bisexual men,and blood donors[J]. J Infect Dis, 1996,174(6) : 1320- 1323. 被引量:1
  • 6Yeo AE, Matsumoto A, Shih JW, et al. Prevalence of hepatitis G virus in patients with hemophilia and their steady female sexual partners[J]. Sex Transm Dis,2000,27(3):178-82. 被引量:1
  • 7Fuglsang T,Fouchard JR,Ege PP. Prevalence of HIV and hepatitis B and C among drug addicts in the city of Copenhagen [ J ]. Ugeslr Laeger, 2000,162(27) :3860-4. 被引量:1
  • 8Levine OS, Vlahov D, Koehler J, et al. Seroepidemiology of hepatitis B virus in a population of injecting drug users. Association with drug injection pattems[J ]. Am J Epidemol, 1995,142 (3): 331-41. 被引量:1
  • 9Garfein RS, Vlahov D, Galai N, et al. Viral infections in short-term injection drug users: the prevalence of the hepatitis C, hepatitis B, human immunodeficiency, and human T-lymphotropic viruses[ J ]. Am J Public Health, 1996,86(5) :655-61. 被引量:1
  • 10Lamden KH, Kennedy N, Beeching NJ, et al. Hepatitis B and hepatitis C virus infections: risk factors among drug users in Northwest England[J]. J Infect, 1998,37(3) :260-9. 被引量:1

引证文献2

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部