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纳络酮治疗中重度新生儿缺氧缺血性脑病的疗效观察

Clinical Observation on Curative Effect of Naloxone for Neonate Hypoxic-ischemic Encephalopathy
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摘要 目的:观察纳络酮治疗中、重度新生儿缺氧缺血性脑病(HIE)的疗效。方法:对25例HIE患儿应用纳络酮静脉注射和静脉点滴,连用3d。结果:治疗组总有效率为92%,对照组总有效率64%(P<0.05)。结论:纳络酮治疗HIE疗效显著,未见毒副作用发生。 Objective: To evaluate the curative effect of naloxone for treating severe neonate hypoxic-ischemic. encephalopathy (HIE) .Methods:25 cases with HIB in treatment group were administrated with naloxone for three days,whereas 25 cases with HIE in control group only received other commonly used drugs.Results:The total effective rate was 92% in treatment group who were treated with naloxon,and 64% in the control group.There was a great difference (P <0.05) .Conclusion:Naloxone is effective in treating severe HIE.There were not toxic reaction.
出处 《医学理论与实践》 2002年第9期997-998,共2页 The Journal of Medical Theory and Practice
关键词 纳络酮 治疗 新生儿 缺氧缺血性脑病 疗效观察 Naloxone,Neonate,HIE,β-endorphin
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