摘要
目的探讨肝上皮样血管平滑肌脂肪瘤(hepatic epithelioid angiomyolipoma,HEAML)的临床特征、诊断、治疗与预后。方法通过1例中年女性HEAML的报道,分析其临床资料并复习相关文献。结果本例患者女性,44岁,体检时发现肝脏占位,无明显临床症状。行腹腔镜肝肿瘤切除术,肉眼可见肝Ⅵ段处一外生型肿瘤,大小约20 mm×15 mm×16 mm,呈暗红色,其包膜完整,与周围组织界限清楚。镜下可见呈圆形、多边形的肿瘤细胞,部分肿瘤细胞胞质淡染透明,核大、深染,并可见散在脂肪样细胞。术后随访6个月,未见肿瘤复发。结论HEAML是一种罕见的肝脏间叶肿瘤。临床表现缺乏特异性,诊断主要依靠病理学检查。手术切除为主要治疗手段,术后有复发和转移可能,宜严密随访。
Objective To investigate the clinical manifestation,diagnosis,treatment and prognisis of hepatic epithelioid angiomyolipoma(HEAML).Methods The clinical data of a case of HEAML in a woman was observed,and the related literature was reviewed.Results The patient was a 44-year-old woman with no clinical symptoms.Medical examination found the liver tumor.TheⅥsegmental type exogenous tumor was visible by the laparoscopic hepatectomy.The size of the tumor was about 20 mm×15 mm×16 mm,which was kermesinus coloured.Its envelope was complete and the boundary was clear.Microscopically,reveal the circular and polygons of tumor cells,part of the tumor cell cytoplasm was light coloured transparent,big nuclear,hyperchromatic,and visible in the fat cells.During the follow-up of 6 months,there was no tumor recurrence.Conclusion The hepatic epithelioid angiomyolipoma is a rare mesenchymal tumors.There is no specificity in clinical manifestations.Diagnosis depends mainly on the histopathological characteristics and immunohistochemical features.Surgical excision is major method but recurrence or metastases is possible,longer follow-up is needed.
作者
王仲
姜家康
连树林
WANG Zhong;JIANG Jiakang;LIAN Shulin(Department of Surgery,Affiliated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China;Department of Oncology,The First Affi liated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China)
出处
《长春中医药大学学报》
2019年第4期746-749,共4页
Journal of Changchun University of Chinese Medicine
基金
吉林省教育厅课题项目(2018)
