摘要
目的探讨弥散张量成像(DTI联合弥散加权成像(DWI)在诊断急性脑梗死(ACI)缺血半暗带(IP)中的应用价值。方法对70例ACI患者行磁共振DWI、DTI扫描,按发病时间将患者分为超急性期(6h内)组与急性期(6-24h内)组,对核心梗死区、IP区表观扩散系数(ADC)、各项异性指数(FA)、平均扩散系数(DCavg)及各参数相对健侧的rADC值、rFA值、rDCavg值进行统计分析。结果 ACI患者梗死核心区ADC值、FA值、DCavg值均明显低于镜像对侧区(P<0.05)。IP区ADC值、FA值、DCavg值均明显高于梗死核心区(P<0.05)。脑梗死IP区ADC值、FA值、DCavg值较健侧均出现降低,且急性期rADC值、rFA值、rDCavg值均明显低于超急性期(P<0.05)。rADC值与rFA值、rDCavg值均呈正相关(r=0.589、0.685,P<0.05),rFA值与rDCavg值呈正相关(r=0.612,P<0.05)。结论 MR-DWI获取的ADC值及DTI获取的FA值、DCavg值可能成为判定IP的重要手段。
Objective To investigate the application value of diffusion tensor imaging(DTI)combined with diffusion-weighted imaging(DWI)in the diagnosis of acute cerebral infarction(ACI)ischemic penumbra(IP).Methods Seventy patients with ACI who underwent magnetic resonance DWI and DTI scans were divided into hyperacute(6 h)group and acute(6-24 h)group according to the onset time.The apparent diffusion coefficient(ADC)values,anisotropic indexes(FA)and average diffusion coefficients(DCavg)of core infarction area and IP area,the rADC value,rFA value and rDCavg value of the contralateral side were statistically analyzed.Results ADC values,FA values and DCavg values of the core infarction area in patients with ACI were significantly lower than those in the contralateral area(P<0.05).The ADC values,FA values and DCavg values of the IP area were significantly higher than those in the core infarction area(P<0.05).The ADC value,FA value and DCavg value of the cerebral infarction IP area were lower than those of the contralateral side.The rADC value,rFA value and rDCavg value in acute stage were significantly lower than those in hyperacute stage(P<0.05).The rADC value was positively correlated with the rFA value and rDCavg value(r=0.589,0.685,P<0.05),and the rFA value was positively correlated with the rDCavg value(r=0.612,P<0.05).Conclusion The ADC value obtained by MR-DWI and the FA value and DCavg value obtained by DTI may be an important means to determine IP.
作者
张迷
杨燕
郑卫华
ZHANG Mi;YANG Yan;ZHENG Wei-hua(Department of Neurology,Wuhan Central Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430000,Hubei Province,China;不详)
出处
《中国CT和MRI杂志》
2019年第8期15-17,共3页
Chinese Journal of CT and MRI
关键词
脑梗死
缺血半暗带
弥散张量成像
弥散加权成像
Cerebral Infarction
Ischemic Penumbra
Diffusion Tensor Imaging
Diffusion-Weighted Imaging
