摘要
目的探讨Pentacam和Orbscan Ⅱ在筛查和诊断圆锥角膜中最敏感的地形图指标。方法选取(2014年9月至2016年12月屈光不正患者)正常组60眼和圆锥组20眼,分别进行Pentacam及Orbscan Ⅱ检查,对Pentacam所检测的指标角膜最薄点厚度(TP)、前表面最小曲率(K1)、前表面最大曲率(K2)、角膜前表面最佳拟合球面曲率半径(ABFS)、角膜后表面最佳拟合球面曲率半径(PBFS)、角膜前表面高度(前Diff值)、角膜后表面高度(后Diff值)和Orbscan Ⅱ所检测的指标角膜最薄点厚度(TP)、最小模拟角膜曲率(Sim K's Min)、最大模拟角膜曲率(Sim K's Max)、角膜前表面最佳拟合球面曲率半径(ABFS)、角膜后表面最佳拟合球面曲率半径(PBFS)、角膜前表面高度(前Diff值)、角膜后表面高度(后Diff值)进行分析,分别比较这些参数在正常对照组和圆锥角膜组之间的差异,寻找Pentacam及Orbscan Ⅱ中最敏感的指标,对比两种仪器在筛查和诊断圆锥角膜的敏感性。结果 Pentacam和Orbscan Ⅱ所检测指标中正常组和圆锥组之间的数据差异均有统计学意义,(P <0. 05)。对各项测量参数分别作ROC受试者工作曲线,并计算曲线下面积可知Pentacam中诊断圆锥角膜的敏感地形图指标有TP、前Diff值和后Diff值; Orbscan Ⅱ中诊断圆锥角膜的敏感地形图指标有TP和后Diff值。结论诊断圆锥角膜时Pentacam中最为敏感的指标为TP、前Diff值和后Diff值; Orbscan Ⅱ中最为敏感的指标为TP和后Diff值。且Pentacam的诊断敏感性要更加优于Orbscan Ⅱ。
Objective To explore the most sensitive topographical indices in the screening and diagnosis of keratoconus with Pentacam and Orbscan Ⅱ. Methods A total of 60 eyes of patients from the control group and 20 eyes of those from keratoconus group who received treatment from September 2014 to December of 2016 were selected for Pentacam and Orbscan Ⅱ examination. The thinnest point （TP） of corneal thickness, mininmnl curvature of the anterior surface of the cornea （ K1 ）, maxinum curvature of the anterior surface of the cornea （ K2 ）, best fit spherical surface radius of curvature of the anterior surface of the cornea （ABFS） , best fit spherical surface radius of curvature of the posterior surface of the cornea （PBFS）, cliff values of cornea anterior surface （pre-Diff value） and cliff values of cornea posterior surface （post-Diff value） detected by Pentacam, as well as TP, minimum simulated corneal curvature （SimK＇ s Min） , maximum simulated corneal curvature （SimK＇s Mac）, ABFS, PBFS, pre-Diff value and post-Diff value detected by the Orbscan Ⅱ were analyzed and compared between normal controls and keratoconus group. The most sensitive indices were explored in diagnosis of keratoconus by Pentacam and Orbscan Ⅱ , and the sensitivity of the two instruments in screening and diagnosis of keratoconus was compared. Results There were significant differences in the indicators measured by Pentacam and Orbscan Ⅱ between the control group and keratoconus groups （P 〈 0.05）. The receiver operating curve （ROC） was calculated for each measurement parameter, and the area under the curve was calculated. It was found that the sensitive topographic indices of keratoconus by using Pentacam included TP, pre-Diff value and post-Diff value, and those for diagnosis of keratoconus by using Orbscan Ⅱ included TP and post-Diff values. Conclusion The most sensitive indicators in diagnosing keratoconus by Pentacam include TP, pre-Diff and post-Diff values and those by Orbscan Ⅱ inclu
作者
隋瑶
邢建男
赵海霞
SUI Yao;XING fiannan;ZHAO Haixia(Department of Ophthalmology,Affiliated Hospital of Inner Mongolia Medical Untiversity,Inner Mongolia Autonomous Region,Hohhot 010050,China)
出处
《河北医药》
CAS
2018年第24期3691-3695,共5页
Hebei Medical Journal
基金
国家自然科学基金项目(编号:81460090)
内蒙古自治区"草原英才"产业创新人才团队工程(2015)
