摘要
目的分析辽宁省肿瘤医院2015—2017年中药注射剂的使用情况以及变化趋势,为制定安全有效的中药注射剂使用规章制度提供科学依据。方法收集2015—2017年辽宁省肿瘤医院中药注射剂使用数据,分析销售金额、用药频度(DDDs)、限定日费用(DDC)以及药品排序比;采用回顾性分析方法,随机抽取辽宁省肿瘤医院2015—2017年使用金额排名前5的中药注射剂100例,分析其用药合理性。结果中药注射剂的用药金额呈现逐年增长趋势,但占药品销售总金额比例上升幅度不大。康艾注射液的使用量稳居第1位,康莱特注射液的用药金额逐年上升,排名由第5位上升到第3位。康艾注射液的DDDs逐年增加,2017年超过参麦注射液,跃升为第1位。醒脑静注射液、喜炎平注射液、消癌平注射液、康莱特注射液的DDC值偏高,连续3年稳居前4位。大多数中药注射剂的排序比接近于1.00。中药注射剂的使用存在适应证不适宜、重复用药、溶媒选择不当等情况。结论 2015—2017年辽宁省肿瘤医院中药注射剂的使用总体上比较合理,但仍存在一些不合理用药现象,有待继续通过临床药师干预、处方医嘱点评、合理用药宣教等手段规范用药行为,保障患者用药的安全、有效和经济。
Objective To analyze the usage and variation tendency of traditional Chinese medicine injections in Liaoning Cancer Hospital and Institute from 2015 to 2017, so as to provide a scientific basis for formulating safe and effective rules and regulations for clinical rational drug use. Methods Consumption sum, defined daily doses（DDDs）, defined daily cost（DDC）, and drug sequence ratio of traditional Chinese medicine injections in Liaoning Cancer Hospital and Institute from 2015 to 2017 were analyzed statistically. A retrospective analysis method was used to sample randomly the top 5 traditional Chinese medicine injections（100 cases） in Liaoning Cancer Hospital and Institute from 2015 to 2017, and the rationality of drug use was analyzed. Results Consumption sum of traditional Chinese medicine injections showed an increasing trend year by year. But the ratio of consumption sums of traditional Chinese medicine injections in all drugs was stable. The amount of Kangai Injection always ranked the first. Consumption sums of Kanglaite Injection increased year by year, and the sequence was from the fifth to the third. DDDs of Kangai Injection increased year by year, and exceeded Shenmai Injection in 2017, and jumped to the first place. DDC of Xingnaojing Injection, Xiyanping Injection, Xiaoaiping Injection, and Kanglaite Injection were high, and always ranked the top four for three years. The drug sequence ratio of most traditional Chinese medicine injections was equal to 1.00. There are indications such as unsuitable indications, repeated use of drugs, and improper choice of solvents in the use of Chinese medicine injections. Conclusion From 2015 to 2017, the use of traditional Chinese medicine injections in Liaoning Cancer Hospital and Institute is generally reasonable, but there are still some phenomena of irrational use of drugs. It is necessary to continue to regulate drug use behaviors through clinical pharmacist interventions, prescription medical opinion, and rational drug education, to ensure the safety,
作者
黄丹雪
刘广宣
黎苏
HUANG Dan-xue;LIU Guang-xuan;LI Su(Department of Pharmacy,Cancer Hospital of China Medical University,Liaoning Cancer Hospital and Institute,Shenyang 110042,China)
出处
《现代药物与临床》
CAS
2018年第11期3026-3031,共6页
Drugs & Clinic
关键词
中药注射剂
限定日剂量
用药频度
限定日费用
排序比
合理性
traditional Chinese medicine injection
defined daily dose
frequency of drug use
average daily cost
drug sequence ratio
rationality
