摘要
炎症性肠病(IBD)是一种易复发的慢性肠道炎症疾病,对人和动物危害极大,迄今没有可根治的药物。作为一种天然产物,小檗碱具有丰富的生理功能和独特的药理特性,治疗IBD的能力不俗,具有防治IBD的潜在优势。本文介绍小檗碱的种类和性质、IBD的基本特征,探讨小檗碱对IBD的调控机制,为其在实践中的应用提供科学依据。
Inflammatory bowel diseases（IBD） is a kind of recurrent and chronic inflammatory disorders of the gut,and is extremely harmful to human and animals.To date,there is no drug to cure for IBD.As a kind of natural product,berberine has an array of physiological functions as well as special pharmacological properties,and has a specific IBD therapeutic potential because of its therapeutic value for IBD.In this review,the species and properties of berberine were presented,and the basic characteristics of IBD was analyzed,finally the regulation mechanisms of berberine on IBD was discussed.This review provided some scientific evidences for the application of berberine in the practice.
作者
郭乙冰
汪水平
刘国威
周承福
GUO Yibing;WANG Shuiping;LIU Guowei;ZHOU Chengfu(College of Animal Science,Southwest University,Chongqing 402460,China)
出处
《动物营养学报》
CAS
CSCD
北大核心
2018年第11期4363-4368,共6页
CHINESE JOURNAL OF ANIMAL NUTRITION
关键词
小檗碱
炎症性肠病
调控机制
berberine
inflammatory bowel disease
regulation mechanism
