摘要
目的:探讨自发性脑脊液鼻漏伴与不伴空泡蝶鞍的临床特点及诊治。方法:回顾性分析51例自发性脑脊液鼻漏患者的临床资料,比较不伴空泡蝶鞍的自发性脑脊液鼻漏与伴空泡蝶鞍的自发性脑脊液鼻漏患者的一般特征、漏口位置以及治疗效果。结果:自发性脑脊液鼻漏患者女性发病明显高于男性,BMI较正常值高;51例患者中5例保守治疗好转后出院,46例接受鼻内镜手术,其中4例复发,且均伴空泡蝶鞍,手术修补成功率为91.3%;伴空泡蝶鞍组年龄、高血压比例以及手术复发例数比例明显高于不伴组,均差异有统计学意义(P<0.05);2组漏口位置均最多见于筛顶,漏口位置差异无统计学意义(P>0.05)。结论:自发性脑脊液鼻漏在肥胖中年女性中常见,漏口以筛顶最多见,鼻内镜下修补成功率高,伴空泡蝶鞍术后更易复发。
Objective：To investigate the clinical characteristics and the diagnosis and treatment of spontaneous cerebrospinal fluid rhinorrhea with and without empty sella.Method：Retrospective analysis clinical data of 51 patients with spontaneous cerebrospinal fluid rhinorrhea,comparison of non-empty sella syndrome of spontaneous cerebrospinal fluid rhinorrhea with empty sella syndrome of spontaneous cerebrospinal fluid rhinorrhea patients with general characteristics,localization and treatment effect.Result：The incidence of spontaneous cerebrospinal fluid rhinorrhea patients was higher in females than in males,BMI index was higher than the normal value.Of these 51 patients,5 of them were discharged after conservative treatment.Endoscopic sinus surgery was performed in 46 cases,of which 4 cases recurred and all had empty sella syndrome,the success rate of surgical repair was 91.3%.The age of empty sella group,the proportion of high blood pressure and the number of patients with surgical recurrence were significantly higher than those in the non-empty sella group（P〈0.05）.The defect locations of two groups were most common in the ethmoid roof,there were no statistically significant differences in each defect location（P〉0.05）.Conclusion：The spontaneous cerebrospinal fluid leak was common in obese middle-aged women,most common defect location in ethmoid roof,nasal endoscopic repair success rate was high,with empty sella surgery were more likely to recur.
作者
王诗毅
汪银凤
孙敬武
WANG Shiyi;WANG Yinfeng;SUN Jingwu(Department of Otolaryngology Head and Neck Surgery,Anhui Medical University,Anhui Provincial Hospital,Hefei,230001,China)
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2018年第22期1707-1710,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
脑脊液鼻漏
空泡蝶鞍
内镜外科手术
spontaneous cerebrospinal fluid rhinorrhea
empty sella
endoscopic surgical procedures
