摘要
目的探讨ABCD3-I评分法结合纤维蛋水平白原检测对短暂性脑缺血发作(TIA,Transient ischemic attack)短期发生脑梗死的风险进行评估。方法用ABCD3-I评分法和ABCD^3-I评分法+纤维蛋白原水平分别测定200例TIA患者的评分,并观察TIA后7d内脑梗死的发生率。结果 200例TIA患者中7d内发生脑梗死的有27例。ABCD3-I评分组中低危组(0～3分)、中危组(4～7分)、高危组(8～13分)TIA患者7d内脑梗死发生率分别为3.23%、11.63%和29.27%(P<0.05),ABCD3-I评分+Fib水平组中低危组(0～3分)、中危组(4～7分)、高危组(8～13分)TIA患者7d内脑梗死发生率分别为3.23%、9.92%和30.61%(P<0.05)。ABCD3-I评分法和ABCD3-I评分法+纤维蛋白原水平检测的ROC曲线下面积(95%CI)分别为0.66(0.56～0.77)和0.69 (0.59～0.80)。ABCD3-I评分法和ABCD^3-I评分法+纤维蛋白原水平组的评分与脑梗死发生率呈线性相关,相关系数分别为0.23、0.26(P<0.05)。结论 ABCD3-I评分能够较为准确地对TIA患者7d内发生缺血性脑梗死的风险进行预测,结合纤维蛋白原水平检测更能为准确地预测脑梗死的发生风险。
Objective To investigate the clinical value of ABCD^3-I score combined with Fib in identifying transient ischemic attack patients at early risk of cerebral infarction.Methods 200 TIA patients were evaluated according to ABCD^3-Icriteria and ABCD^3-I＋ Fib criteria.The occurrences of stroke were observed in7 days.Results 200 TIA patients were included in the study.The number of stroke occurrence within 7 days after TIA were 27.The 7-day risk of stroke was 3.23%in patients with an ABCD^3 score of low risk（0～3）,11.63% with a score of moderate risk（4～7）,and 29.27% with a score of high risk（8～13）（P〈0.05）.The7-day risk of stroke was 3.23%in patients with an ABCD^3-I＋Fib score of low risk（0～3）,9.92% with a score of moderate risk（4～7）,and 30.61% with a score of high risk（8～13）（P〈0.05）.In the ABCD^3-I criteria and ABCD^3-I＋ Fib criteria the area under the curve and 95% Confidence Interval for predicting stroke risk within 7 days after TIA were 0.66（0.56～0.77）、0.69（0.59～0.80）respectively.There was linear correlation between the ABCD^3-I criteria and ABCD^3-I＋Fib criteria.The correlation coefficients were 0.23 and 0.26 respectively.Conclusion ABCD^3-I criteria was accurate to predict the occurrence of cerebral infarction in 7 days of TIA.ABCD^3-I＋Fib criteria was more accurate to predict the occurrence of cerebral infarction in short-term of TIA.
作者
王静
常龙
Wang Jing;Chang Long(Department of Neurology,Hospital 463 of PLA,Shenyang 110000)
出处
《卒中与神经疾病》
2018年第5期533-537,共5页
Stroke and Nervous Diseases
