摘要
缺血性卒中是威胁人类健康的严重疾病,最主要的病因是动脉粥样硬化。上游治疗是控制疾病首发和复发的危险因素,缺血性卒中的上游治疗是未来工作的重心。控制血压、抗血小板治疗、抗凝治疗及调节血脂治疗均能明显降低卒中的风险,控制血压是预防缺血性卒中的关键,也是未来工作的重中之重。研究表明,心房颤动是心源性缺血性卒中的主要病因。目前高危人群和卒中患者的危险因素控制并不理想,需要提高临床医师对风险因素的认识,并根据临床证据选择合适的治疗措施。希望通过更多的大型临床试验探知治疗风险和潜在的益处,期望更多的卒中预防试验研究提供新的临床证据。
Ischemic stroke is a serious disease that threatens human health. The main cause is atheroselerosis. Upstream treatment is to control the risk factors for the onset and recurrence of the disease,which will become the emphasis in the future. Controlling blood pressure,antiplatelet therapy, anticoagulant therapy and regulating blood lipids can efficiently reduce the risk of stroke, and control of blood pressure is the key for the prevention. Studies have shown that atrial fibrillation is a major cause of cardiac isehemie stroke. The control of the risk factors of high-risk group and stroke patients is not satisfactory for the time being, so the clinicians should raise awareness of the risk factors,and select appropriate treatments based on the clinical evidence. It＇s hoped that there will be more large-scale clinical trials to ascertain the risks and potential benefits of treatment, and more stroke prevention studies to provide new clinical evidence.
作者
赵晓彬
袁如玉
ZHAO Xiaobin;YU-AN Ruyu(Department of Cardiology,the Second Hospital of Tianjin Medical University,Tianjin 300211,China)
出处
《医学综述》
2018年第22期4374-4379,4384,共7页
Medical Recapitulate
关键词
缺血性卒中
上游治疗
高血压
心房颤动
Ischemic stroke
Upstream therapy
Hypertension
Atrial fibrillation
