摘要
目的探讨颅-锁骨发育不全综合征(cleidocranial dysplasis, CCD)的临床及影像表现,以提高对本病的认识。方法回顾性分析本院确诊的2例CCD典型病例的临床及影像表现,结合文献对该病的临床特征及影像表现进行总结分析。结果 2例患者有不同程度的颅骨、牙齿、锁骨发育障碍,主要表现为颅骨发育异常、牙颌面畸形、锁骨发育不全和"锥形"胸等。结论 CCD具有较特征性临床及影像表现,有助于临床诊断。
Objective To investigate the clinical features and radiologic findings of cleidocranial dysplasis（CCD）. Methods Two patients with a clinically verified CCD were reviewed retrospectively. Results All patients expressed developmental abnormality of crania, teeth and clavicle. The radiologic features of CCD are：（1）multiple impacted permanent and supernumerary teeth, hypoplastic maxillary sinus and slender coronoid process.（2）open sutures of the skull, small maxillary sinuses, missing nasal bone, numerous wormian bones, large fontanelles, hypoplastic maxilla, and prognathic mandible.（3）dysplasia of both the clavicles and cone shaped thorax. Conclusion Clinical and radiologic characteristics of CCD are distinctive in certain extent, wich help the diagnosis.
作者
邹亚楠
林聪
田昭俭
ZOU Ya-nan;LIN Cong;TIAN Zhao-jian(Department of Oral and Maxillofacial Surgery,Shengli Oil-feld Central Hospital,Dongying 257034,Shandong Province,China)
出处
《罕少疾病杂志》
2018年第5期16-18,89,共4页
Journal of Rare and Uncommon Diseases
基金
国家临床重点专科建设项目建设项目(国卫办医函[2013]544号)
