摘要
目的:探讨原发性高血压病人血清胃蛋白酶原Ⅰ(PGⅠ)、胃蛋白酶原Ⅱ(PGⅡ)水平及两者比值的变化。方法:选择原发性高血压住院病人107例进行空腹采集静脉血,采用酶联免疫法定量检测血清PGⅠ和PGⅡ浓度水平,比较2组PG结果差异。结果:单纯原发性高血压组和高血压合并胃炎组病人血清PGⅠ和PGⅡ水平明显高于对照组(P <0. 01);而2组病人血清PGⅠ和PGⅡ比值与对照组相比,差异均无统计学意义(P> 0. 05)。结论:血清PGⅠ和PGⅡ浓度水平明显升高,提示临床医生在排除胃部疾病的情况下,可能与原发性高血压的发生有关。
Objective： To investigate the changes of serum levels of pepsinogen Ⅰ and pepsinogen Ⅱ,and its ratio in patients with primary hypertension. Methods： The serum levels of pepsinogen Ⅰ and pepsinogen Ⅱ of fasting venous blood in 107 patients with primary hypertension were detected using enzyme-linked immunosorbent assay,and the difference of which between two groups was compared. Results： The serum levels of pepsinogen Ⅰ and pepsinogen Ⅱ in patients with primary hypertension were significantly higher than those in control group（ P〈0. 01）. The difference of the ratio of pepsinogen Ⅰ and pepsinogen Ⅱ between two groups was not statistically significant（ P〈0. 05）. Conclusions： The serum levels of pepsinogen Ⅰ and pepsinogen Ⅱ in patients with primary hypertension significantly increase,which may be related to the primary hypertension under excluding stomach diseases.
作者
梁友宝
王中安
常滋毓
吴珊珊
衡二虎
LIANG You-bao;WANG Zhong-an;CHANG Zi-yu;WU Shan-shan;HENG Er-hu(Department of Laboratory,The First People＇s Hospital of Bengbu,Bnegbu Anhui 233000,China)
出处
《蚌埠医学院学报》
CAS
2018年第11期1499-1500,1504,共3页
Journal of Bengbu Medical College
基金
安徽省蚌埠市科技局指导项目(20160311)
