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冠状动脉分叉病变经皮冠状动脉介入治疗中分支血管闭塞的影响因素分析 被引量:4

The Influencing Factors Analysis of Branch Vessel Occlusion in Percutaneous Coronary Intervention for Paients with Coronary Bifuraction Lesions
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摘要 目的探讨冠状动脉分叉病变经皮冠状动脉介入(percutaneous coronary intervention,PCI)治疗中分支血管闭塞的影响因素。方法选择2015年3月至2017年5月收治的冠状动脉分叉病变患者95例,收集患者基本资料和影像学资料,分析冠状动脉分叉病变PCI治疗中分支血管闭塞的情况,同时依次采用单因素分析和多因素Logistic回归分析确定冠状动脉分叉病变PCI治疗中分支血管闭塞的影响因素。结果 PCI治疗的冠状动脉分叉病变患者分支血管闭塞发生率为24.21%(23/95);依次采用单因素和多因素Logistic回归分析法确定分叉角度、斑块分布同侧、斑块不规则、主支心肌梗死溶栓试验(TIMI)血流分级、分支TIMI血流分级及主支/分支参考血管直径比(MV/SB)是冠状动脉分叉病变患者分支血管闭塞的影响因素。结论行PCI治疗的冠状动脉分叉病变患者合并分支血管闭塞的发生率较高,其中高分叉角度、斑块分布同侧、斑块形状不规则、主支和分支TIMI血流分级低及MV/SB大会增加患者发生分支血管闭塞的风险。 Objective To investigate the influence factor of coronary artery occlusion in the treatment of coronary artery occlusion. Methods From March 2015 to May 2017,95 patients with coronary bifurcation lesions were selected. The basic and imaging data were collected to analyze the occlusion of branch vessels during PCI for coronary bifurcation lesions. The influence factors of occlusive vascular interventional treatment were analyzed by using single factor analysis and multifactor Logistic regression analysis method in turn. Results The incidence of branch occlusion was 24.21%(23/95)in 95 patients with coronary bifurcation lesions treated with PCI,and the bifurcation angle,plaque distribution on the same side,plaque irregularity,main branch thrombolytic test(TIMI)blood flow classification,branch TIMI blood flow classification and main branch/branch were determined by univariate and multivariate logistic regression analysis in turn. The branch reference vessel diameter ratio(MV/SB) is a risk factor for branch occlusion in patients with coronary bifurcation disease. Conclusion The incidence of merging branches of vascular occlusion patients with coronary bifurcation lesions of interventional treatment is high. High bifurcation angle,ipsilateral plaque distribution,irregular plaque shape,low TIMI classification of main and branch blood flow and bigger MV/SB increase the risk of branch occlusion.
作者 柴志强 卢树苹 乔翠峰 CHAI Zhiqiang;LU Shuping;QIAO Cuifeng(Third Department of Cardiology,the First Hospital of Zhangjiakou,Zhangjiakou 175000;Second Department of Cardiology,the First Hospital of Zhangjiakou,Zhangjiakou 175000;Department of Otorhinolarynogology,the First Hospital of Zhangjiakou,Zhangjiakou 175000)
出处 《宁夏医科大学学报》 2018年第8期924-928,共5页 Journal of Ningxia Medical University
关键词 冠状动脉分叉病变 经皮冠状动脉介入 分支血管闭塞 影响因素 coronary artery bifurcation lesions interventional therapy branch occlusion influence factor
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