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肝细胞癌组织β-人绒毛膜促性腺激素的表达

Expression of Human Chorionic Gonadotropin-β in Hepatic Cellular Carcinoma
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摘要 目的 检测肝细胞癌(HCC)组织中β-人绒毛膜促性腺激素(β-HCG)的表达。方法 用免疫组织化学(SP)的方法,检测51例HCC中β-HCG的表达。结果 51例HCC中有42例呈阳性,占82%;β-HCG的表达与血清AFP水平、肿瘤大小、单发或多发、是否伴有肝硬化和坏死、分化程度、门静脉癌栓形成、复发、肝外转移等均无显著相关性(P>0.05)。结论 HCC组织可以表达β-HCG,这种表达与肝癌的生物学行为可能无明显关系。 Objective To investigate the expression of human chorionic gonadotropin-β in hepatic cellular carcinoma (HCC) .Methods The β-HCG of 51 cases of HCC was detected with immunohistochemistry.Results The expressive rate of β-HCG was 82% .There was no relation between the expression of β-HCG and the level of AFP of serum, size of mass, single or multiple nodes,with or without cirrhosis,with or without necrosis,differentiation,with or without carcinoma embolus,recurrence and metastasis ( P > 0.05) .Conclusion HCC may express β-HCG,and the expression of β-HCG may have no relation with the biological behaviors of HCC.
出处 《岭南现代临床外科》 2000年第2期90-91,共2页 Lingnan Modern Clinics in Surgery
关键词 肝肿瘤 人绒毛膜促性腺激素 免疫组织化学 Hepatic neoplasm Human chorionic gonadotropin Immunohistochemistry
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  • 1Susan L. Naylor,William W. Chin,Howard M. Goodman,Peter A. Lalley,Karl-Heinz Grzeschik,Alan Y. Sakaguchi. Chromosome assignment of genes encoding theα andΒ subunits of glycoprotein hormones in man and mouse[J] 1983,Somatic Cell Genetics(6):757~770 被引量:1

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