摘要
目的探讨^(18)F-氟脱氧葡萄糖(^(18)F-FDG)正电子发射计算机断层成像(PET)行心肌代谢显像时不同血糖调节方法对其显像成功率的影响。方法选取自2013年8月至2018年4月收治的拟诊为心肌缺血的患者83例为研究对象。对拟行^(18)F-FDG PET心肌代谢显像的受检者根据血糖水平给予葡萄糖负荷,如果受检者血糖值>8.8 mmol/L,则注射胰岛素调整血糖值至7.9~8.8 mmol/L,纳入A组;如果血糖值为7.9~8.8 mmol/L,则纳入B组。比较A、B两组患者的显像成功率。结果进行血糖调节后,A组显像成功41例,显像失败3例,显像成功率为93.2%(41/44)。B组显像成功29例,显像失败10例,显像成功率为74.4%(29/39)。A组显像成功率显著高于B组,两组比较,差异有统计学意义(P<0.05)。结论 ^(18)F-FDG PET心肌代谢显像时,应使用先葡萄糖负荷后胰岛素调整的方法进行血糖调节,可获得更好的图像。
Objective To investigate the effects of different blood glucose regulation methods on the success rate of myocardial metabolic imaging in ^18F-FDG PET.Methods A retrospective study was performed on 83 cases of patients with myocardial ischemia who were admitted from August 2013 to April 2018.Patients who underwent ^18F-FDG PET myocardial metabolic imaging were given glucose load according to their blood glucose level.If the blood glucose level of subjects was more than 8.8 mmol/L,insulin was injected to adjust the blood glucose level to 7.9-8.8 mmol/L,which was included in Group A.If the blood glucose level is 7.9-8.8 mmol/L,which was included in Group B.The success rate of imaging was compared between Group A and Group B.Results After the adjustment of blood glucose,41 cases of successful imaging and 3 cases of failure of imaging were successfully performed in Group A,with success rate of 93.2%（41/44）.In Group B,there were 29 successful cases and 10 failed cases,and the success rate was 74.4%（29/39）.The success rate of imaging in Group A was significantly higher than that in Group B,and the difference was statistically significant （ P 〈0.05）.Conclusion ^18F-FDG PET myocardial metabolic imaging,glucose adjustment should be used after the glucose adjustment method for blood glucose regulation to get better images.
作者
吴锐先
王治国
郭佳
张宗鹏
石庆学
左峰
张国旭
郝珊瑚
WU Rui-xian;WANG Zhi-guo;GUO Jia;ZHANG Zong-peng;SHI Qing-xue;ZUO Feng;ZHANG Guo-xu;HAO Shan-shan(Department of Nuclear Medicine,General Hospital of Northern Theater Command,Shenyang 110016,China)
出处
《临床军医杂志》
CAS
2018年第11期1282-1284,共3页
Clinical Journal of Medical Officers
基金
辽宁省自然科学基金(2012225019)
