摘要
急性呼吸窘迫综合征(ARDS)是ICU常见的综合征之一,病死率高,诊断率较低,其诊断标准一直在更新,对这一综合征作出简便准确的诊断是我们一直追求的目标。从AECC标准到柏林标准,均不能准确的识别ARDS患者,临床上仍存在误诊,ARDS的临床诊断与病理学诊断之间存在一定的差距。近年来多种生物标志物被证实与ARDS的发病相关,但依据特异性生物标志物诊断ARDS仍面临挑战。ARDS诊断目前仍没有一个金标准,但临床+生物标志物诊断模式是ARDS诊断的努力方向。
ARDS is the common syndrome in ICU with high mortality and low diagnostic rate. The diagnostic criteria of ARDS kept updating and its concise and correct diagnosis is always our aim to pursuit. ARDS patients could not be correctly recognized by AECC criteria even Berlin criteria and clinical misdiagnosis always exists. Clinical diagnosis is inconsistent with pathological diagnosis. Recentl)~ a myriad of biomarkers has been proved to be relevant to pathogenesis of ARDS, however, ARDS diagnosis dependent on certain biomarker still faces challenge. No gold standard has been established in ARDS diagnosis, and clinical manifestation combined with biomarker is the direction forth on.
作者
黄丽丽
刘玲
邱海波
HUANG Li-li;LIU Ling;QIU Hai-bo(Department of Critical Care Medicine,Zhongda Hospital Affiliated to Southeast University,Nanjing 210009,China)
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2018年第11期977-980,共4页
Chinese Journal of Practical Internal Medicine
基金
国家自然科学基金(81571847)
国家科技重大专项课题(2017ZX10103004)
江苏省医学重点学科(实验室)(ZDXKA2016025)
科技部应急专项项目
关键词
急性呼吸窘迫综合征
acute respiratory distress syndrome