摘要
目的对比观察复方丹参注射液与丹参川芎嗪注射液分别治疗急性胰腺炎患者临床疗效及安全性。方法将80例急性胰腺炎的患者随机分为2组,每组40例。在基础治疗基础上,A组给予复方丹参注射液治疗,B组给予丹参川芎嗪注射治疗,观察治疗后总体疗效及治疗前及5天后血淀粉酶、白介素6及C反应蛋白变化;腹痛及腹胀缓解时间;平均住院时间;并发症发生率。结果 A组患者的治疗有效率为92. 50%,低于B组患者的95. 00%。2组数据间具有显著差异(P <0. 05)。A组与B组在治疗前血淀粉酶、白介素6及C反应蛋白相比较无显著性差异(P> 0. 05); 2组治疗5天后血淀粉酶、白介素6及C反应蛋白显著低于各组治疗前水平,B组治疗5天后血淀粉酶、白介素6及C反应蛋白显著低于A组,B组治疗后腹痛缓解时间、腹胀缓解时间及平均住院时间均短于A组,B组治疗后并发症发生率为10. 0%低于A组的15. 0%,差异均具有统计学意义(P <0. 05)。结论丹参川芎嗪注射液治疗急性胰腺炎的效果是肯定的,值得临床应用推广。
Objective To compare the clinical efficacy and safety of compound Danshen injection and Salviae Miltiorrhizae and Ligustrazine Hydrochloride injection in the treatment of acute pancreatitis. Method 80 patients with acute pancreatitis were randomly divided into two groups,with 40 cases in each group. On the basis of basic treatment,group A was treated with compound salvia miltiorrhiza injection,and group B was given injection of Salvia miltiorrhiza and ligustrazine. The overall effect after treatment and the changes of blood amylase,interleukin 6 and C reactive protein before and 5 days after treatment,the time of abdominal pain and abdominal distention,the average time of hospitalization and the incidence of complications were observed. Results The effective rate of group A was 92. 50%,which was lower than that of group B（95%）. There was a significant difference between the two groups（P〈0. 05）. There was no significant difference in blood amylase,IL-6 and C reactive protein in group A and group B before treatment（P〈0. 05）. The blood amylase,IL-6 and C reactive protein in the two groups were significantly lower than those before treatment for 5 days. The blood amylase,IL-6 and C reactive protein in the group B were significantly lower than that of the group A after 5 days of treatment,and the abdominal pain in the group B after treatment.The remission time,the remission time of abdominal distention and the average length of hospitalization in the group B were shorter than those in the A group,and the incidence of complications after treatment in group B（10%） was lower than that in group A（15%）,and the difference was statistically significant（P〈0. 05）. Conclusion The effect of Salviae Miltiorrhizae and Ligustrazine Hydrochloride injection in treating acute pancreatitis is affirmative and worthy of clinical application and promotion.
作者
郭凯
GUO Kai(Grade 2016 Graduate, the First Clinical School, Hubei University of Chinese Medicine, Hubei Province, Wuhan 430060, China)
出处
《光明中医》
2018年第20期2983-2985,共3页
GUANGMING JOURNAL OF CHINESE MEDICINE
关键词
急性胰腺炎
丹参川芎嗪
复方丹参注射液
微循环障碍
Acute pancreatitis
Salvia Ligustrazine
Compound salvia mihiorrhiza injection
Microcirculation disorder
