摘要
目的:探讨损伤控制术对急性腹部创伤患者临床结局、炎症反应的影响。方法:取急性腹部创伤患者500例,随机数字法分为对照组(n=250)和观察组(n=250)。对照组采用确定性手术治疗,观察组采用损伤控制术治疗,比较两组临床结局及对炎症反应的影响。结果:观察组术后DIC、休克、MODS及死亡发生率,均明显低于对照组(P<0.05);观察组术后血清C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)和白细胞介素-6(IL-6)水平,均明显低于对照组(P<0.05)。结论:急性腹部创伤患者采用损伤控制术治疗效果理想,值得推广应用。
Objective ： To explore the application effect of damage control surgery in patients with emergency abdominal trauma and its effect on clinical and inflammatory response. Methods： 500 patients with emergency abdominal trauma were selected, and randomly divided into control group （n=250） and observation group （n=250）. The control group was treated with deterministic surgery, while the observation group was treated with damage control surgery. The clinical effect and inflammatory response were compared between the two groups. Results ： The incidence of DIC, shock, MODS and mortality in the observation group was significantly lower than those in the control group （all P〈0.05）. The levels of CRP, TNF-α, IL-1 β and IL-6 in the observation group were significantly lower than those in the control group （all P〈 0.05）. Conclusion ： The use of damage control surgery number in the treatment of emergency abdominal trauma is ideal and worthy to be popularized.
作者
朱颉
陆燕华
边白央拉
ZHU Jie;LU Yan-hua;Bianbaiyangla(Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou,510120;Heahh Service Center of Zhongba County,Xigaze,Tibet)
出处
《岭南急诊医学杂志》
2018年第5期422-424,共3页
Lingnan Journal of Emergency Medicine
关键词
损伤控制术
急性腹部创伤
临床效果
炎症反应
damage control surgery
emergency abdominal trauma
clinical effect
inflammatory response
