摘要
目的采用Meta分析的方法评价磁共振DWI序列评估小肠克罗恩病活动性的价值。方法检索Pub Med、Web of Science、Cochrane Library、Embase、中文科技期刊全文数据库、中国数字化期刊数据库及中国期刊全文数据库,纳入有关DWI序列评估克罗恩病活动性的中英文文献,对最终纳入文献进行质量评价和数据提取。使用STATA 12. 0软件进行统计分析,检验各研究间的异质性,绘制森林图和合并受试者工作特征曲线(SROC)并计算曲线下面积(AUC)。结果最终纳入10篇文献进行Meta分析,包括906处小肠肠段病变。DWI序列诊断小肠克罗恩病活动性的合并敏感度为0. 91(95%CI 0. 77-0. 97);合并特异度为0. 91(95%CI 0. 80-0. 96),AUC为0. 96。结论磁共振DWI序列评估小肠克罗恩病活动性的敏感度和特异度均较高,为对比剂禁忌证的患者、年轻患者以及需要长期随访观察的患者提供了另一种检查方式。
Objective To investigate the value of DWI sequences in evaluating the activity of Crohn＇ s disease in the small intestine using Meta-analysis. Methods PubMed, Web of Science, Cochrane Library, Embase, CNKI, Wangfang, and CBM were searched. The studies on DWI sequence in evaluation of the activity of Crohn＇ s disease were included. Statistical analysis was conducted using STATA 12. 0 software. The smnmary receiver operating characteristic curves（SROC） and the area under the curve（AUC） were used to evaluate diagnostic accuracy values of included studies. Results Ten articles were included for Meta-analysis, including 906 small intestinal lesions. The pooled sensitivity of the DWI sequence was 0. 91 （95 % CI 0. 77 -0. 97 ）, and the pooled specificity was 0. 91 （95 % CI 0. 80 -0. 96） and the AUC was 0. 96. Conclusion DWI sequence has a higher sensitivity and specificity for evaluating the activity of Crohn＇ s disease in the small intestine. MilI provides an alternative method for patients with contrast eontraindieations, young patients, and patients who require long-term follow-up.
作者
张沥
李陇超
王睿
折霞
张鑫
宦怡
ZHANG Li;LI Longchao;WANG Rui;ZHE Xia;ZHANG Xin;HUAN yi(Department ofMRI,Shaanxi Provincial People＇s Hospital,Xi＇an 710000,China;Department of Radiology,Xijing Hospital,Air Force Military MedicalUniversity;Department of Radiology,Xidian Group Hospital)
出处
《山西医科大学学报》
CAS
2018年第11期1354-1358,共5页
Journal of Shanxi Medical University
基金
陕西省重点研发计划一般项目-社会发展领域(2018SF-169)
关键词
DWI
MRI
小肠
克罗恩病
META分析
diffusion weighted imaging
magnetic resonance imaging
small intestine
Crohn＇ s disease
Meta-analysis
