摘要
目的:观察西黄胶囊联合吉西他滨治疗晚期宫颈癌的临床疗效。方法:将186例晚期宫颈癌患者随机分为对照组和观察组各93例。对照组给予吉西他滨化疗,观察组给予吉西他滨化疗联合西黄胶囊口服治疗。观察2组局部复发、远处转移及不良反应发生情况,比较2组治疗总有效率。结果:观察组局部复发及远处转移率均低于对照组,差异均有统计学意义(P <0.05)。观察组骨髓抑制及消化道反应发生率均低于对照组,差异均有统计学意义(P <0.05)。观察组总有效率69.89%,对照组总有效率59.14%,2组比较,差异有统计学意义(P <0.05)。结论:西黄胶囊联合吉西他滨治疗晚期宫颈癌,效果优于单独使用吉西他滨。
Objective： To observe the clinical effect of Xihuang capsules, combined with gemcitabine for advanced cervical cancer. Methods： Divided 186 cases of patients with advanced cervical cancer into the control group and the observation group randomly, 93 cases in each group. The control group received gemcitabine for chemotherapy, while the observation group additionally received the oral administration of Xihuang capsules. Observed the local recurrence, distant metastasis and occurrence of adverse reactions in both groups, and compared the total effective rate of both groups. Results： The local recurrence rate and distant metastasis rate in the observation group were both lower than those in the control group, differences being significant （P 〈 0.05）. The incidence of myelosuppression and gastrointestinal reaction in the observation group was respectively lower than that in the control group, differences being significant （P 〈 0.05）. The total effective rate was 69.89% in the observation group and 59.14% in the control group, difference being significant （P 〈 0.05）. Conclusion： The clinical effect of Xihuang capsules combined with gemcitabine for advanced cervical cancer is better than the simple application of gemcitabine.
作者
彭敏
马丽娟
王幼辉
张静
王锡恩
PENG Min;MA Lijuan;WANG Youhui;ZHANG Jing;WANG Xi＇en
出处
《新中医》
CAS
2018年第11期169-171,共3页
New Chinese Medicine
关键词
宫颈癌
晚期
中西医结合疗法
西黄胶囊
吉西他滨
复发
转移
疗效
Cervical cancer
Advanced stage
Integrated Chinese and western medicine therapy
Xihuang capsules
Gemcitabine
Recurrence
Metastasis
Clinical effect
