摘要
目的:观察小青龙汤治疗外寒内饮型咳嗽变异性哮喘的临床疗效。方法:将96例患儿随机分为2组各48例,对照组给予止咳、吸氧、化痰、平喘等基础治疗,并加用孟鲁斯特钠咀嚼片口服,观察组在对照组的基础上加用小青龙汤治疗,2组均治疗28天;观察2组临床疗效、临床症状改善时间、复发率及不良反应发生情况。结果:临床总有效率观察组为89.58%,对照组为75.00%,2组比较,差异有统计学意义(P <0.05)。观察组患者哮喘持续发作时间、咳嗽消失时间、肺部哮鸣音和体征消失时间均短于对照组,差异有统计学意义(P <0.05)。复发率观察组为8.33%,对照组为22.92%,2组比较,差异有统计学意义(P <0.05)。不良反应发生率观察组为4.17%,对照组为10.41%,2组比较,差异有统计学意义(P <0.05)。结论:小青龙汤联合西药常规治疗外寒内饮型咳嗽变异性哮喘疗效显著,能明显改善患儿临床症状,缩短治疗时间,降低复发率,且安全性较高。
Objective： To observe the clinical effect of Xiaoqinglong tang for cough variant asthma with external cold and internal fluid type. Methods. Divided 96 cases of children patients into two groups randomly, 48 cases in each group. The control group received the oral administration of Montelukast chewable tablets and such basic treatment as relieving cough, inhaling oxygen, resolving phlegm and relieving asthma, while the treatment group additionally received Xiaoqinglong tang. The treatment for both groups lasted for 28 days. Observed the clinical effect, improvement time of clinical symptoms, recurrence rate and occurrence of adverse reactions in both groups. Results： The clinical total effective rate was 89.58% in the observation group and 75.00% in the control group, difference being significant （P 〈 0.05）. The continuous attack time of asthma, disappearance time of cough and disappearance time of pulmonary wheezing and signs in the observation group were all shorter than those in the control group, difference being significant （P 〈 0.05）. The recurrence rate was 8.33% in the observation group and 22.92% in the control group, difference being significant （P 〈 0.05）. The incidence of adverse reactions was 4.17% in the observation group and 10.41% in the control group, difference being significant （P 〈 0.05）. Conclusion： Xiaoqinglong tang combined with routine western medicine has significant effect in treating cough variant asthma with external cold and internal fluid type. It can evidently improve the clinical symptoms of patients, shorten the treatment time, and reduce the recurrence rate with relatively high safety.
作者
应华娜
施伟国
YING Huana;SHI Weiguo
出处
《新中医》
CAS
2018年第11期82-84,共3页
New Chinese Medicine
关键词
咳嗽变异哮喘
外寒内饮型
中西医结合疗法
小青龙汤
Cough variant asthma
External cold and internal fluid type
Integrated Chinese and western medicine therapy
Xiaoqinglong tang
