摘要
目的:为了研究血塞通片中起主要作用的三七皂苷的质量标准,控制药品质量。方法:通过高效液相色谱法在流动相甲醇-水(50:50)条件下测定血塞通的溶解度、熔点、精密度、稳定性确定质量标准。结果:对三七总皂苷进行了含量测定和方法学考察实验,检测三批中试样品的结果与标准要求相符。结论:控制三七皂苷的含量是血塞通片在控制质量标准的关键,应进一步控制血塞通质量标准中有关物质和溶剂残留等检测指标。
Objective： In order to study the quality standard of the notoginsenoside which is the main function in Xuesaitong tablet,the quality of the medicine was controlled. Methods： The total content of notoginsenoside was determined by HPLC method and the method of methodological investigation. The results of three batches of pilot samples were consistent with the standard requirements.Results： The control of the content of notoginsenoside saponin is the key to control the quality standard of Xuesaitong tablet. The indexes of the related substances and residual solvents in Xuesaitong quality standard should be further controlled.
作者
张玮
徐霜
韩颂
Zhang Wei(Heilongjiang Food and Drug Information Center（Harbin 150001)
出处
《黑龙江医药》
CAS
2018年第5期952-954,共3页
Heilongjiang Medicine journal
关键词
血塞通片
质量标准
研究
Xuesaitong tablet
quality standard
Research
